زنگنه, اکرم

دانشگاه رازی

[ 1 ] - اثرات حفاظتی عصاره الکلی سورانه (Allium saralicum R.M. Fritsch) بر مسمومیت کبدی القاء‌شده با تتراکلریدکربن در موش سوری

Background and Objective: Due to their anti-oxidant and anti-inflammatory compounds, medicinal plants can protect the liver against hepatotoxicant induced injuries. The aim of this study was to evaluate the protective effects of Allium Saralicum R.M. Fritsch (ASRMF) on CCl4- induced hepatotoxicity in mice. Materials and Methods: In the present experimental study, 35 male mice were divided in...

[ 2 ] - Evaluation of Nephroprotective and Antidiabetic Effects of Gundelia tournefortii Aqueous Extract on Diabetic Nephropathy in Male Mice

Background and objectives: Due to the rapid growth of global interest in use of ethno medicinal plants, their effects and safety assessment have become substantial. Gundelia tournefortii has been used as antioxidant, anti-inflammatory, antipyretic, anti-fungal, and antibacterial agent. In the present study, nephrprotective and antidiabetic properties of Gundelia to...

[ 3 ] - ارزیابی اثرات ضد دیابتی و محافظت کبدی عصاره آبی برگ گیاه استویا( Stevia rebaudiana )( قسمت شیرین) در موش سوری دیابتی شده با استرپتوزوتوسین

Introduction:  Stevia rebaudiana has been recently known as an antioxidant, antiflammatory, and antimicrobial agent. Hepatoprotective and antidiabetic properties of the aqueous extract of S. rebaudiana on diabetic mice has been assessed in the present study. Methods:  Diabetes was induced by administration of 60 mg/kg of streptozotocin intraperitoneally in 35 mature male mice and they were r...

[ 4 ] - Ameliorative property of the ethanolic extract of Tragopogon graminifolius DC. on carbon tetrachloride-induced hepatotoxicity in mice: A pharmacological examination

ABSTRACT Hepatotoxicity is the most common disorder with severe effects on quality of life. Tragopogon graminifolius DC. has been used in Iran as an astringent and bleeding inhibitor, wound healer and gastro-protector agent. To our knowledge, there are little evidence at hand on hepatoprotective activity of T. graminifolius. The present study was carried out to assess hepatoprotective propert...

[ 5 ] - Protection of alloxan monohydrate-induced testicular toxicity by Gundelia tournefortii aerial parts aqueous extract in male mice.

ABSTRACT For a long period, ethno medicinal plants have been a valuable source of natural products for maintaining human health, especially in the last decade, with more intensive studies for natural therapies. The use of ethno medicinal plant for pharmaceutical purposes has gradually increased in Iran. Gundelia tournefortii has been used as an antibacterial, anti-fungal, antipyretic, anti-in...

[ 6 ] - A Stereological and Biochemical Examination: Hepatoprotective Activity of Anthemis odontostephana Boiss. Ethanol Extract Against CCl4-Induced Hepatotoxicity in Mice

Background and objectives: In Iranian traditional medicine, Anthemis odontostephana Boiss has been used in treating gastric ulcers, diabetes, and inflammatory diseases. In the present study, hepatoprotective activity of A. odontostephana ethanol extract (AOEE) on carbon tetrachloride (CCl4)-induced hepatotoxicity in male mice has been evaluated.  <s...

[ 7 ] - Assessment of the Hepatoprotective Activity of Tragopogon graminifolius DC. Aqueous Extract on CCl4- Induced Hepatotoxicity in Mice

Background and objectives: Tragopogon graminifolius DC. is widely used in Iranian traditional medicine as a gastro-protective and wound healer agent.  In the present study the hepatoprotective property of T. graminifolius DC. aqueous extract (TGAE) was investigated against carbon tetrachloride (CCl4) induced hepatocellular injury in mice. Me...

[ 8 ] - A Comparative Evaluation of Nephroprotective Property of Urtica dioica L. Aqueous Extract and Glibenclamide in Diabetic Mice

Background and objectives:Diabetes is the most common metabolic disorder with severe effects on quality of life. Decreasing serum glucose levels and normalization of kidney parameters is of great clinical importance for treating diabetes. Urtica dioica L. has been used in as anti-inflammatory, antioxidant, anti-fungal, and antibacterial agent. To our knowledge, there a...

[ 9 ] - Stereological and biochemical studies of kidney in diabetic mice treated with ethanolic extract of Urtica dioica L.: Introducing an anti-diabetic and nephroprotective agent

Urtica dioica L. is widely used as an anti‑inflammatory, antioxidant, antimicrobial, hypocholesterolemic, antiulcer, anti‑colitis, anticancer, hypotensive, immunomodulatory, and hepatoprotective agent. In the present study, the antidiabetic and nephroprotective potentials of U. dioica ethanolic extract was investigated against streptozotocin (STZ) induced diabetic mice. Male mice were divided i...

[ 10 ] - Chemical characterization and anti-parasitic property of essential oil of Coriandrum sativum leaf against Trichomonas vaginalis

Coriandrum sativum has been used in Iranian traditional medicine as an anti-inflammatory, antioxidant, antibacterial, and antifungal agent. The purpose of this study was to evaluate the chemical composition and anti-parasitic property of essential oil of C. sativum leaf on trophozoite of Trichomonas vaginalis. C. sativum was collected from Kermanshah city and essential oil was prepared by the C...