نصرتی, مختار

دانشگاه اصفهان، اصفهان، ایران

[ 1 ] - غربالگری بیوانفورماتیکی مهارکننده‌(های) پروتئاز NS3/4A ویروس هپاتیت سی از دو گیاه دارویی Cornus officinalis و Syzygium aromaticum

Background: The hepatitis C virus (HCV) infection is a major global health problem and one of the common causes of mortality worldwide. Therefore, currently many studies have been focused on introducing novel and effective anti HCV agents especially plant materials. Therefore, the study was aimed to screening novel HCV protease inhibitor(s) from two medicinal plants including Cornus officinalis...

[ 2 ] - A Novel Multi-Epitope Vaccine For Cross Protection Against Hepatitis C Virus (HCV): An Immunoinformatics Approach

Background: Hepatitis C virus (HCV) causes acute and chronic human hepatitis infections. Due to the high genetic diversity and high rates of mutations in the genetic material so far there is no approved vaccine against HCV. Materials and Methods: The aim of this study was to determination B and T cell conserved epitopes of E1 and E2 proteins from HCV and construction of a chimeric pepti...

[ 3 ] - Bioinformatics Study of the Effects of Some Phytocompounds Found in Ferulago Angulat, Scrophularia Striata and Laurus Nobilis Medicinal Plants on Inhibition of the Proteins Causing Antibiotic Resistance in Staphylococcus Aureus: A Descriptive Study

  Background and Objectives: Currently infections caused by Staphylococcus aureus have increased and raised antibiotic resistant isolates. Therefore, lots of studies have been done to introduce novel anti-S.aureus compounds especially natural originated constitutes. Hence, this study aimed to determine bioinformatics screening of novel inhibitors of antibiotic resistance-associated proteins in...

[ 4 ] - In silico design a multivalent epitope vaccine against SARS-CoV-2 for Iranian populations

Background: Due to high genetic variation in human leukocyte antigen )HLA( alleles, epitope-based vaccines don’t show equal efficacy in different human populations. therefore, we proposed a multi-epitope vaccine against SARS-CoV-2 for Iranian populations. Materials and Methods: For this purpose, the proteins without allergenicity and high antigenicity as well as conservancy level from SARS-CoV...