بهرام زاده, سمیه

[ 1 ] - اثر مت‌فورمین بر بیان ژن Pdx-1 طی تکامل پانکراس موش

AbstractIntroduction: Metformin, an oral medicine used to treat type 2 diabetes, is a Glucagon-Like Peptide-1 (GLP-1) analogue, which has been demonstrated to stimulate the expression of Pancreatic duodenal homeobox-1 (Pdx-1), Insulin and Glucose transporter 2 (Glut-2) genes. In this study, the regulatory effect of metformin on beta cells function through the expression of�Pdx-1, Insulin and Glut…