Mohsen Yaghoubi

Clinical Knowledge Management Unit, Department of Community Medicine, Iran University of Medical Science, Tehran, Iran.

[ 1 ] - Acellular pertussis vaccine efficacy: An updated systematic review and meta –analysis

Background: Recent studies indicate an increased incidence of pertussis disease in recent years. The aim of this study was to evaluate the efficacy of the acellular vaccine for children (as a replacement of current whole cell vaccine in the Expanded Program on Immunization) and for high-risk adults in Iran through updating current best available evidence.   Methods: We performed a syste...

[ 2 ] - Health technology assessment of non-invasive interventions for weight loss and body shape in Iran

Background: The burden of obesity and diet-related chronic diseases is increasing in Iran, and prevention and treatment strategies are needed to address this problem. The aim of this study was to determine the outcome, cost, safety and cost-consequence of non-invasive weight loss interventions in Iran.   Methods: We performed a systematic review to compare non-invasive interventions (cr...

[ 3 ] - The cost effectiveness of dynamic and static interspinous spacer for lumbar spinal stenosis compared with laminectomy

Background: The present study aims to evaluate the cost-effectiveness of Dynamic Interspinous Spacer (Coflex®) and Static Spacer (X-STOP ®) compared to Laminectomy (LAMI) in patients with lumbar spinal stenosis.   Methods: A decision-analysis model was developed to estimate the cost-effectiveness. The effectiveness parameters were obtained from a systematic literature review in ...

[ 4 ] - Clinical outcome of autologous mononuclear cells transplantation for spinal cord injury: a systematic review and meta-analysis

  Background :Cell-based therapies can be used to treat neurological diseases and spinal cord injuries. The aim of this study was to assess the clinical outcome of bone marrow derived mononuclear cells (BM-MNCs) transplantation in patients with spinal cord injuries.   Method s: Following a systematic review to detect clinical intervention studies, a meta-analysis was done for pooling data to es...