Chidambaram Venil

[ 1 ] - Production of L-Asparaginase by Serratia marcescens SB08: Optimization by Response Surface Methodology

This paper describes optimization method that combines the Plackett-Burman design, a factorial design and the response surface method, which were used to optimize the medium for the production of L-asparaginase by Serratia marcescens SB08. Four medium factors, from out of 11 medium factors, were screened by Plackett-Burman design experiments and subsequent optimization process to find out the o...