Mohammad Ali Eghbal
Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. |Department of Pharmacology and Toxicology, School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
[ 1 ] - Mechanistic approach for thioridazine-induced hepatotoxicity and potential benefits of melatonin and/or coenzyme Q10 on freshly isolated rat hepatocytes
Thioridazine (TZ) is used mainly in the treatment of schizophrenia. However, hepatotoxicity as a life-threatening adverse effect is associated with its clinical use. In this context, we examined the cytotoxic mechanisms of TZ on freshly isolated rat hepatocytes to better understanding of the pathogenesis of TZ-induced hepatotoxicity. Hepatocytes were prepared by the method of collagenase enzyme...
[ 2 ] - Mechanistic approach for thioridazine-induced hepatotoxicity and potential benefits of melatonin and/or coenzyme Q10 on freshly isolated rat hepatocytes
Thioridazine (TZ) is used mainly in the treatment of schizophrenia. However, hepatotoxicity as a life-threatening adverse effect is associated with its clinical use. In this context, we examined the cytotoxic mechanisms of TZ on freshly isolated rat hepatocytes to better understanding of the pathogenesis of TZ-induced hepatotoxicity. Hepatocytes were prepared by the method of collagenase enzyme...
نویسندگان همکار