Hossein Bordbar

Department of Anatomical Sciences, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

[ 1 ] - Modulatory Effect of Gonadotropins on Rats’ Ovaries after Nandrolone Decanoate Administration: A Stereological Study

Background: Nandrolone decanoate (ND) is an anabolic androgenic steroid (AAS) which influences the ovarian structure and function. We assessed the effects of ND on the ovarian volume, number of primordial follicles, and level of hormones and also evaluated the modulatory effects of gonadotropins on the histopathological changes imposed by the administration of ND. Methods: Six groups of Sprague...

[ 2 ] - Apoptosis, Autophagy, and Necrosis in Murine Embryonic Gonadal Ridges and Neonatal Ovaries: An Animal Model

Background: In mammalian ovaries, loss of over two-thirds of germ cells happens due to cell death. Nonetheless, the exact mechanism of cell death has yet to be determined. The present basic practical study was designed to detect 3 types of programmed cell death, namely apoptosis, autophagy, and necrosis, in murine embryonic gonadal ridges and neonatal ovaries.Methods: Twenty gonadal ridges and ...

[ 3 ] - Protective Effect of Human Menopausal Gonadotropins on Rat Ovarian Structure Following Use of Nandrolone Decanoate: From a Histological Standpoint

Background and Aim: Nandrolone decanoate is known as one of the most destructive environmental factors in the reproductive system in men and women. In this study, we assessed the protective effect of gonadotropins (hMG) on histological changes of rat ovarian structure. Materials and Methods: 50 female rats were divided into 5 groups, including control, nandrolone decanoate (ND), hMG, ND + hMG, ...