Hongxing Cai

Department of Forensic Medicine, Xuzhou Medical University, Xuzhou, Jiangsu 221002, China

[ 1 ] - Akt inhibitor deguelin aggravates inflammation and fibrosis in myocarditis

Objective(s): Myocarditis is characterized by inflammatory cell infiltration in myocardial stroma. Attenuation of tumor necrosis factor (TNF)-α and interleukin (IL)-1β is a reliable mark for improving the prognosis. Protein kinase B (Akt) plays an important role in the development and progression of myocarditis. The specific role of the natural inhibitor of Akt, Deguel...

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