Mehdi Shakouri Khomartash

Shahid Fallahi Polyclinic, AJA University of Medical Sciences, Tehran, Iran

[ 1 ] - CEA Plasmid as Therapeutic DNA Vaccination against Colorectal Cancer

Background: Human colorectal cancer cells overexpress carcinoembryonic antigen (CEA). CEA is a glycoprotein which has shown to be a promising vaccine target for immunotherapy against colorectal cancer. Objective: To design a DNA vaccine harboring CEA antigen and evaluate its effect on inducing immunity against colorectal cancer cells in tumor bearing mice. <str...