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Seham Abdel-Gaber

Department of Pharmacology, Faculty of Medicine, Minia University, 61511 Minia, Egypt

[ 1 ] - Ameliorative effects of silymarin on HCl-induced acute lung injury in rats; role of the Nrf-2/HO-1 pathway

<em><strong>Objective(s):</strong></em> Aspiration is a common cause of acute lung injury (ALI), which lacks an effective treatment. Inflammation and oxidative stress play key roles in ALI development. Silymarin is an active extract of Silybum marianum plant seeds (milk thistle). Silymarin has potent anti-inflammatory and antioxidant effects; however its role in aspiration induced ALI has not b...