Deepak Bhatia
Department of Pharmacogenomics, Bernard J. Dunn School of Pharmacy, Shenandoah University- ICPH Fairfax, Fairfax, VA 22031, USA
[ 1 ] - First Total Synthesis and Pharmacological Potential of a Plant Based Hexacyclopeptide
A new bioactive proline-rich cyclohexapeptide - diandrine C (6), previously isolated from whole plant of Drymaria diandra (Caryophyllaceae), was synthesized through coupling reactions of tetrapeptide unit Boc-Gly-l-Pro-l-Tyr-l-Trp-OH with dipeptide unit l-Pro-Gly-OMe using N,N-diisopropylcarbodiimide (DIPC) as the coupling agent, followed by cyclization of l...
[ 2 ] - First Total Synthesis and Pharmacological Potential of a Plant Based Hexacyclopeptide
A new bioactive proline-rich cyclohexapeptide - diandrine C (6), previously isolated from whole plant of Drymaria diandra (Caryophyllaceae), was synthesized through coupling reactions of tetrapeptide unit Boc-Gly-l-Pro-l-Tyr-l-Trp-OH with dipeptide unit l-Pro-Gly-OMe using N,N-diisopropylcarbodiimide (DIPC) as the coupling agent, followed by cyclization of l...
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