Seyed Ali Jehbez
Department of Applied Chemistry, Shiraz Branch, Islamic Azad University, P.O. Box 71993-5, Shiraz, Iran
[ 1 ] - Catalyst-Free One-Pot Four-Component Synthesis of 3-(Imino)-pyrrolo[2,1-a]isoquinolines in Glycerol: Two Different Products through Two Different Purification Methods
The one-pot four component synthesis of 3-(Imino)-2,3-dihydropyrrolo[2,1-a]isoquinoline-1,1(10bH)-dicarbonitrile derivatives via a catalyst-free reaction between aryl aldehydes, malononitrile, isoquinoline and isocyanides was successfully conducted in glycerol as a benign, nontoxic and biodegradable promoting reaction medium. The progress of the reaction with two different common purification m...
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