Sirati-Sabet, Majid
Shahid Beheshti University of Medical Sciences
[ 1 ] - THE EFFECT OF QUINACRINE ON THE EXPRESSION OF WNT3A GENE IN MDA-MB 231 AND MCF7 BREAST CANCER CELL LINES
Background & Aims: Triple-negative breast cancer cells refer to any breast cancer that does not express the genes for the estrogen, progesterone, and HER2 receptors. The Wnt signaling pathway is important in the development and progression of various types of cancers. Quinacrine, a derivative of 9-aminoacridine, has been shown to inhibit the growth of several types of cancer cells. In this stud...
[ 2 ] - Effect of Medium-Chain Triglycerides on Gene Expression of ATP-Citrate Lyase and H3K27ac in Developing Non-Alcoholic Fatty Liver Disease in an Animal Model
Background and purpose: Increase in ATP-dependent Citrate Lyase (ACLY) is observed in individuals with nonalcoholic fatty liver disease (NAFLD). One of the compounds considered for the prevention of fatty liver is Medium chain triglycerides (MCT). In this study, the preventive effect of MCT on ACLY enzyme gene expression and the level of histone 3 lysine 27 acetylation (H3K27ac) were investigat...
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