bardania, hassan

Yasuj University of Medical Sciences

[ 1 ] - Hydro-alcoholic extract of Dorema aucheri loaded on liposome nanoparticles, effectively induces apoptosis in SW48 cell line

Background & aim: Several natural products have been introduced to protect against a wide range of cancers including colorectal cancer. Dorema aucheri has traditionally been used as an herbal medicine and its extract has been reported to contain significant amounts of antioxidants Such as flavonoids, anthocyanins and phenolic acid. This study aimed to evaluate the cytotoxic and apoptotic effect...

[ 2 ] - The effect of podophyllotoxin as an inducer of apoptosis using molecular docking method

Background and aim: Podophyllotoxin is used as one of the main treatments for genital warts. It is a precursor of etoposide and teniposide, which is used in the treatment of various cancers. Despite a large number of cancer studies, the exact mechanism of podophyllotoxin remains unknown. Chemotherapy drugs reduce cancer cells by inducing apoptosis. The regulation of the apoptotic pathway has be...

[ 3 ] - Cytotoxicity and Apoptotic Effect of Nanoliposomes loaded with curcumin and miR-34a on MCF-7 and HT29 Cell Lines

Background and aims Colorectal and breast cancers are among the most important causes of mortality in the world. In spite of several attempts, their treatment is yet faced with several problems. Therefore, identification of novel therapeutic approaches is needed. Anti-cancer effects of curcumin and miR-34a have been proposed in various studies. Regarding their pro-apoptotic effects in cancer c...