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[ 1 ] - P-232: Evaluation of Cilostamide Efficiency in Comparison with Forskolin on The Two-Step In Vitro Maturation of Mice Germinal Vesilce Oocytes

Background: The effects of cumulus cells and the effectiveness of a PDE3 specific inhibitor (Cilostamide) in comparison with an adenylate cyclase activator (Forskolin) on the maturation rate and developmental competence of mouse germinal vesicle (GV) oocytes were evaluated Materials and Methods: Germinal vesicles (GV) oocytes of PMSG-primed mice were divided into cumulus denuded oocytes (CDOs) ...

[ 2 ] - P-233: The Effect of Cumulus Cells in Biphasic In Vitro Maturation of Mice Germinal Vesicle Oocytes in The Presence of Alpha Lipoic Acid

Background: The efficiency of in vitro maturation (IVM) has remained low despite extensive effort to understand the culture conditions. This study investigated the effect of cumulus cells and meiotic inhibitors on oocyte developmental competence in the presence of Alpha Lipoic acid (ALA) Materials and Methods: Mouse germinal vesicle oocytes were considered in cumulus-denuded oocytes (CDOs) and ...

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