Kwasi Bugyei
Department of Medical Pharmacology, University of Ghana Medical School, College of Health Sciences, University of Ghana, Korle Bu-Accra, Ghana.
[ 1 ] - Glycine/NMDA Receptor Pathway and Mediating the Rapid-Onset Antidepressant Effect of Alkaloids From Trichilia Monadelpha
Introduction: Major depressive disorder is often associated with suicidal tendencies, and this condition accentuates the need for rapid-acting antidepressants. We previously reported that alkaloids (ALK) from Trichilia monadelpha possess antidepressant action in acute animal models of depression and that this effect is mediated through the monoamine and L-arginine-NO-cGMP pathways. This study i...
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