Sunil K Gupta

Post Graduate Institute of Medical Education and Research (PGIMER), Department of Neurosurgery, Chandigarh, India.

[ 1 ] - Reelin Signaling Pathway and Mesial Temporal Lobe Epilepsy: A Causative Link

Introduction: Mesial temporal lobe epilepsy (MTLE) is the most frequent form of partial epilepsy. Granule cell dispersion, resulting from aberrant neuronal migration in the hippocampus, is pathognomonic of MTLE. Reelin, a secreted neurodevelopmental glycoprotein has a crucial role in controlling the radial migration of neurons. Several animal studies have implicated Reelin in the MTLE pathogenesi…

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