حسین اکبری

استادیار گروه آموزشی آمار زیستی و اپیدمیولوژی، دانشگاه علوم پزشکی کاشان، ایران

[ 1 ] - مقایسه شیوع کم خونی فقر آهن در افراد آلوده و غیر آلوده به هلیکوباکتر پیلوری در شهرستان کاشان

مقدمه: عفونت هلیکو باکترپیلوری از عفونت‌های شایع می‌باشد که عوارض متعددی دارد. بررسی‌ها به تاثیر این عفونت در کاهش جذب آهن بدلیل کاهش ترشح اسید معده و به تبع آن بروز کم خونی اشاره کرده‌اند. در این مطالعه، مقایسه شیوع کم خونی فقر آهن در افراد آلوده و غیر آلوده به هلیکوباکتر پیلوری در شهرستان کاشان مورد بررسی قرار گرفت. مواد و روش‌ها: افرادی که به منظور بررسی آنتی بادی IGg به آزمایشگاه مراجعه کر...

[ 2 ] - Academic Performance, Sleep Disorders and Their Association in Middle School Students in Iran

Background: Although sleep disorders are common problems among families and they affect the learning, memory processes and academic performance of children, there is no evaluation of these disorders in Iran. The aim of this study was to assess the prevalence of sleep disorders and its association with academic performance of school age children.Materials and Methods: A cross-sectional study was...

[ 3 ] - Mutation analysis of connexin 50 gene among Iranian families with autosomal dominant cataracts

Objective(s): Childhood cataract is a genetically heterogeneous eye disorder that results in visual impairment. The aim of this study was to identify the genetic mutations of connexin 50 gene among Iranian families suffered from autosomal dominant congenital cataracts (ADCC). Materials and Methods: Families, having at least two members with bilateral familial congenital cataract, were selected ...

[ 4 ] - Down-regulation of miR-135b in colon adenocarcinoma induced by a TGF-β receptor I kinase inhibitor (SD-208)

  Objective(s):Transforming growth factor-β(TGF-β) is involved in colorectal cancer (CRC). The SD-208 acts as an anti-cancer agent in different malignancies via TGF-β signaling. This work aims to show the effect of manipulation of TGF-β signaling on some miRNAs implicated in CRC. Materials and Methods: We investigated the effects of SD-208 on SW-48, a colon adenocarcinoma cell line. The cell li...

[ 5 ] - Protective effects of celecoxib on inflammatory cytokine levels and testis indices after induction of varicocele

Introduction: Varicocele is a pathological dilation of spermatic cord vein plexus, and celecoxib, an inhibitor of cyclo-oxygenase-2, is widely used in the treatment of chronic inflammation. So, we examined the effects of celecoxib on inflammatory cytokines, testicular Sertoli and spermatogonial cells number, seminiferous tubule diameter, and sperm indices in immature male rats with induced vari...

[ 6 ] - مدل های شکنندگی توام چند متغیره برای مدل‌بندی رخدادهای بازگشتی چندگانه وکاربرد آن در سرطان پستان

Background: Breast cancer is one of the most common recurrence cancers among women. There are several factors that can affect the multiple recurrence of this disease, which have been studied and recognized in various studies, however, with the fact that these factors are known, can not always accurately predict the incidence of metastasis. On the other hand, simultaneous examination of the type...

[ 7 ] - اثرات القاء پلی‌پلوئیدی بر روی خصوصیات موروفولوژیکی، فیزیولوژیکی و بیوشیمیایی گیاه زنیان (Carum carvi L.)

زنیان گیاهی علفی یک‌ساله متعلق به تیره چتریان، دارای اثرات ضد میکروبی و قارچ‌کش بوده که عمده اثرات مربوط به ترکیب تیمول است. القاء پلی‌پلوئیدی با استفاده از مواد شیمیایی جهش‌زا به‌عنوان یکی از روش‌های اصلاح گیاهان دارویی به‌منظور افزایش قابلیت تولید متابولیت‌های ثانویه مورد استفاده قرار گرفته است. بدین منظور جهت بررسی اثرات القاء پلی‌پلوئیدی بر زنیان سیستان آزمایشی به‌صورت فاکتوریل در قالب طرح ...

[ 8 ] - Simultaneous modeling of multiple recurrences in breast cancer patients

Introduction: Breast cancer is one of the most common recurrence cancers among women. There are several factors that can affect multiple recurrence of this disease. On the other hand, simultaneous examination of the types of relapses will make the results more accurate. The purpose of this study was to use a joint frailty model to model multiple recurrences of breast cancer patients. Materials ...

[ 9 ] - Effects of Hesperidin During Pregnancy on Antidepressant-like behaviour in Postpartum Mice

BACKGROUND:Post-partum depression is the most prevalent form of mental illness and herbal therapies are potential alternatives and adjuncts for its treatment. Hesperidin is the major flavonoid isolated from cit- rus fruits which has neuroprotective, antioxidant and antidepressant activity. OBJECTIVES: We studied the effect of exposure to Hesperidin during pregnancy on postpartum antide- pressan...