زهرا رضایی یزدی
-استاد روماتولوژی، مرکز تحقیقات بیماریهای روماتیسمی، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد،مشهد، ایران
[ 1 ] - آدیپوکینازها : رزیستین و بیماریهای روماتیسمی
در سالهای اخیر ،اپیدمی جهانی افزایش وزن منجر به افزایش توجه به شناخت بیولوژی بافت چربی سفید شده است. آدیپوسیت ها و ماکروفاژهای موجود در نسج چربی تولیدکننده چندین پروتئین واسطه ای تحت عنوان آدیپوکین ها است. آدیپوکین ها شامل انواع مختلفی از پپتیدها با خواص پیش التهابی از جمله لپتین ، رزیستین، لیپوکالین 2، اینترلوکین 18 واثرات ضد التهابی مثل آدیپونکتین می باشند. رزیستین یکی از این پپتیدهای جدی...
[ 2 ] - Brain Single Photon Emission Computed Tomography Scan (SPECT) and Functional MRI in Systemic Lupus Erythematosus Patients with Cognitive Dysfunction: A Systematic Review
Objective(s): Systemic lupus erythematosus (SLE) is an autoimmune disease with a wide range of clinical manifestations. Cognitive dysfunction is one of the manifestations that could present prior to the emergence of any other neuropsychiatric involvements in SLE. Cognitive dysfunction is a subtle condition occurring with ahigh frequency. However, there is no data on the correlation of cognitive...
[ 3 ] - H Syndrome Masquerade as Rheumatologic Disease
Background H syndrome is an autosomal recessive genodermatosis with a low prevalence which is caused by a mutation in SLC29A3 gene. This disorder is characterized by sclerotic, hyperpigmented, hypertrichotic cutaneous plaques with systemic involvement including: hepatosplenomegaly, heart anomalies, hearing loss, hypogonadism, low height, and hyperglycemia. Case Presentation Here we have pres...
[ 4 ] - Protective role of HLA-DRB1*11 against juvenile idiopathic arthritis living in North Eastern Iran
Objective(s): Juvenile idiopathic arthritis (JIA) is one of the most common chronic rheumatic diseases in children. The complex nature of this immune-mediated disease owes itself to several predisposing genes and environmental factors affecting its pathogenesis. Conducted in Iran, this study was originally intended to investigate every possible association between HLA DRB1 alleles and a suscept...
[ 5 ] - Metabolic syndrome in lupus patients in northeast of Iran, and their lifestyle habits
Background: Systemic lupus erythematous is an autoimmune disease associated with atherosclerotic manifestations or metabolic disturbance due to inflammation. The aim of this study was to determine frequency of metabolic syndrome (MetS) in SLE compared to healthy controls. Methods: In this cross-sectional study, 150 SLE patients and 220 healthy volunteers were enrolled. MetS was diagnosed acc...
[ 6 ] - تأثیر تمرینات پیلاتس بر شدت درد و شاخص های تعادلی زنان مبتلا به آرتروز زانو
هدف: استئوارتریت زانو یکی از شایع ترین بیماری ها در زنان می باشد که میتواند موجب عوارضی از قبیل درد و کاهش تعادل شود. لذا پیدا کردن راهی که بتواند این عوارض را کاهش دهد، از اهمیت زیادی برخوردار است. با توجه به اثرات مثبت تمرینات پیلاتس، در این تحقیق تأثیر تمرینات پیلاتس بر شدت درد و شاخص های تعادلی زنان مبتلا به استئوآرتریت زانو مورد بررسی قرار گرفت. روش بررسی: تعداد 26 زن مبتلا به استئوآرتریت...
[ 7 ] - Sydenham's Chorea
Sydenham’s chorea is a delayed complication of group Aßhaemolytic streptococcal infections and forms one of the majorcriteria of acute rheumatic fever.It is characterised bychorea, muscular weakness, and a number of neuropsychiatricsymptoms. It is considered to be an autoantibody mediated disorderwith the evidence suggesting that patients with Sydenham’schorea produce antibodies that cross reac...
[ 8 ] - Preoperative Evaluation and Management of Patients Receiving Biologic Therapies
The preoperative care of patients undergoing orthopedic surgery and treated with biologic agents is of great significance.Perioperative use of biologic agents could lead to such complications as infection and delayed postoperative woundhealing. This narrative review aimed to evaluate the current information on the use of biologic agents in patientsundergoing orthopedic surgery...
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