غزاله گرایلی
فیزیک و مهندسی پزشکی، دانشکده پزشکی، دانشگاه علوم پزشکی تهران، ،ایران
[ 1 ] - بررسی شبیه سازی اثرات هایپرترمیای ناشی از کاربرد نانوذرات مغناطیسی بربافت همگن واقع در میدان مغناطیسی خارجی
چکیدهدر مطالعات کلینیکی , مشخص کردن توزیع دما درون بافت سالم و نیز بافت تومورال در طی درمان هایپرترمیا دشوار است. از آن جایی که باحس گر های مرسوم دما تنها در تعداد محدودی مکان اندازه گیری می شود مطالعات شبیه سازی کمک می کند که پزشکان به درک بهتری از این روش درمانی دست پیدا کنند. در این مطالعه، سه مدل تومور دو بعدی بر اساس تصاویر توزیع های نانو ذره در تومورهای PC3، DU145 وLAPC4 در محیط COM...
[ 2 ] - Experimental Evaluation of Depth Dose by Exit Surface Diode Dosimeters for Off-Axis Wedged Fields in Radiation Therapy
Introduction Evaluation of the delivered dose of externally wedged photon beams by external diode dosimeters during the treatment process requires the estimation of exit surface dose correction factors in various wedge angles and field sizes. Materials and Methods A system of absorbed dose evaluation, using p-type diode dosimeters placed on the exit surface of a phantom, was characterized for e...
[ 3 ] - Evaluation of Dose Calculation Algorithms Accuracy for Eclipse, PCRT3D, and Monaco Treatment Planning Systems Using IAEA TPS commissioning tests in a Heterogeneous Phantom
Introduction: The accuracy of dose calculation algorithm (DCA) is highly considered in the radiotherapy sequences. This study aims at assessing the accuracy of five dose calculation algorithms in tissue inhomogeneity corrections, based on the International Atomic Energy Agency TEC-DOC 1583. Material and Methods: A heterogeneous phantom was sc...
[ 4 ] - Penumbra Measurements and Comparison of In-House and Standard Circular Cones by the Gafchoromic Film, Pinpoint Ion Chamber, and MCNPX Monte Carlo Simulation
Introduction: Penumbra is an important property of the radiation beam to obtain a suitable margin surrounding the target volume. Therefore, the precise penumbra width determination in stereotactic radiotherapy is necessary for treatment planning. This study aimed to compare the obtained results of penumbra width by in-house and standard circul...
[ 5 ] - Fabrication of anthropomorphic phantoms for use in total body photon irradiation and total skin electron irradiation studies
Introduction: Total Skin Electron Therapy (TSET) and Total Body Irradiation (TBI) are kinds of treatment which use electron and photon beams to treat special types of cancers. The aim of these techniques are to deliver uniform dose to the entire skin while minimizing delivered dose to organs at risk. To check the homogeneity of dose delivery in TBI and TSET, using a humanoid ph...
[ 6 ] - Comparative Study between Electronic Portal Imaging Device (EPID) and Cone Beam Computed Tomography (CBCT) for Radiation Treatment Verifications
Introduction: Electronic Portal Imaging Device (EPID) and Cone Beam Computed Tomography (CBCT) are the preferred tools of Image Guided Radiotherapy (IGRT) and Dose Guided Radiotherapy (DGRT) which have been used for Radiotherapy treatment verifications. As a result, the number of publications dealing with these two tools for radiation treatment verification has increased consi...
[ 7 ] - Study the effect of source to diaphragm distance (SDD) on beam penumbra width of Gamma Knife machine model 4C using Monte Carlo simulation
Introduction: Stereotactic radiosurgery (SRS) is one of the conformal radiotherapy methods and Gamma Knife is a non-invasive SRS technique to treat intracranial lesions with 201 Co- 60 sources without need to surgery and bleeding. Beam penumbra phenomenon leads to irradiation outside the field and normal tissues. Therefore, considering it is momentous to attain the acceptable t...
[ 8 ] - Comparison of different TBI techniques in terms of dose homogeneity
Introduction: Total body irradiation (TBI) is a form of external beam radiotherapy which is used in conjunction with chemotherapy with the purpose of immunosuppression. Since the target in TBI is the whole body so a uniform dose distribution throughout the entire body during TBI is necessary. As recommended by AAPM dose variation must be within ±10% of prescription dose. A revi...
[ 9 ] - Dosimetry and Radioenhancement Comparison of Gold Nanoparticles in Kilovoltage and Megavoltage Radiotherapy using MAGAT Polymer Gel Dosimeter
Background: Numerous unique characteristics of the nanosized gold, including high atomic number, low toxicity, and high biocompatibility make it one of the most appropriate nanostructures to boost radiotherapy efficacy. Many in-vivo and in-vitro investigations have indicated that gold nanoparticles (AuNPs) can significantly increase tumor injuries in low kilovoltage radiotherapy. While deep-lyi...
[ 10 ] - Physical and Dosimetric Aspect of Euromechanics Add-on Multileaf Collimator on Varian Clinac 2100 C/D
Background:Â Before treatment planning and dose delivery, quality assurance of multi-leaf collimator (MLC) has an important role in intensity-modulated radiation therapy (IMRT) due to the creation of multiple segments from optimization process.Objective: The purpose of this study is to assess the quality control of MLC leaves using EBT3 Gafchromic films.Material and Methods: Leaf Position accur...
[ 11 ] - Investigation of the dose enhancement effect of spherical bismuth oxide nanoparticles in external beam radiotherapy
Introduction: External radiotherapy is the most common method of radiotherapy which the most important problem associated with is that there is no difference between healthy and tumor tissues in dose absorption. One way to differentiate the dose sensitivity is to use metal-based nanoparticles. Bismuth oxide nanoparticles are good candidates for cancer radiotherapy. In this study, we investigate...
نویسندگان همکار
E Gorji 1