Chandra Sekharan
Department of Pharmaceutical Biotechnology & Pharmaceutical analysis, Medarametla Anjamma Mastan Rao College of Pharmacy
[ 1 ] - Spectrophotometric Analysis of Vardenafil in Tablet Dosage Forms by Using Electrophilic Coupling Reagents
Two new spectrophotometric methods (M1 and M2) are developed for the determination of vardenafil in bulk and in tablet dosage forms. The method M1 involves oxidative coupling of vardenafil with 3-methyl-2-benzothiazolinone hydrazone hydrochloride in presence of ferric chloride in acidic medium yielding green colored chromogen with absorption maxima at 625 nm. The method M2 is based on the oxida...
[ 2 ] - Simple spectrophotometric methods for quantification of modafinil using 1,2-naphthoquinone-4-sulphonate and 2,4-dinitrophenol as analytical reagents
Two simple visible spectrophotometric methods are developed and validated for the quantification of modafinil using 1,2-naphthoquinone-4-sulphonic acid (NQS method) and 2,4-dinitrophenol (DNP method) as analytical reagents. The NQS method involves the reaction of modafinil with 1,2-naphthoquinone-4-sulphonate in alkaline medium at room conditions to form a yellow colored product exhibiting maxi...
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