Saeid Amanpour

Center of Cancer Biology Research, Tehran University of Medical Sciences, Tehran, Iran

[ 1 ] - The Characteristics of an Ovine Lymphoid Cell-Line sensitive to Vaccinal Infectious Bursal Disease Virus Strain

Infectious bursal disease (IBD), also known as Gumboro disease, is a globally well-known disease with a significant socio-economic effect. For control of IBD, several commercial egg- and cell-based vaccines are prepared. The cell-based IBD vaccines are significantly cost-effective; however, it is essential to confirm their safety and efficacy. The main cell line used to product the cell-based I...

[ 2 ] - AGS cell line xenograft tumor as a suitable gastric adenocarcinoma model: growth kinetic characterization and immunohistochemistry analysis

Objective(s): Gastric cancer is the third leading cause of cancer-related death worldwide. The overall survival rate of patients is poor because gastric cancers are usually diagnosed at the late stages. Therefore, further research is needed and appropriate research tools are required to develop novel therapeutic approaches.Materials and Methods: Eight female athymic nude mice with a C57BL/6 bac...

[ 3 ] - بررسی اثر مواجهه صدا بر پارامترهای اسپرم (تعداد، تحرک و زنده ماندن) موش سوری

صدا به عنوان یکی از مهمترین آلاینده فیزیکی محیط کار محسوب می­گردد که اثرات زیان­آور آن روی موجودات زنده مکرراً مورد بررسی قرار گرفته‌اند. صدا با ایجاد اثرات منفی روی پارامترهای اسپرم‌ها می­تواند به عنوان عامل مؤثری در تولید مثل محسوب گردد. در این مطالعه 16 سر موش سوری نر در دو گروه مورد و شاهد مورد استفاده قرار گرفتند. صدای مرکب با پهنای 500-8000 هرتز با تراز شدت صوتی 2 ±100 دسی‌بل به مدت 10 روز...

[ 4 ] - Effect of Gamma Irradiation on Microbial Decontamination, Crude Nutrient Content, and Mineral Nutrient Composition of Laboratory Animal Diets

Laboratory animal models are an important part of test design. Certain conditions such as microbial contamination in diets of these models could affect the results of experiments. One of the most important routes that predispose to contamination is generated through feeding of laboratory animals. This study aimed to show the effect of gamma irradiation in reducing bacteria concentrations,...