Fatemeh Norouzi

Neurocognitive Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

[ 1 ] - The effects of Nigella sativa on sickness behavior induced by lipopolysaccharide in male Wistar rats

Objective: Neuroimmune factors contribute on the pathogenesis of sickness behaviors. Nigella sativa (NS) has anti-inflammatory, anti-anxiety and anti-depressive effects. In the present study, the effect of NS hydro-alcoholic extract on sickness behavior induced by lipopolysaccharide (LPS) was investigated. Materials and Methods: The rats were divided into five groups (n=10 in each): (1) control...

[ 2 ] - Protective effects of Nigella sativa on synaptic plasticity impairment induced ‎by lipopolysaccharide

In the present study the protective effect of Nigella sativa (N. sativa)on synaptic plasticity impairment induced by lipopolysaccharide (LPS) in rats was investigated. Fifty-eight rats were grouped and treated as follows: 1) control (saline), 2) LPS, 3) LPS-N. sativa,and 4) N. sativa. In a Morris water maze test, the escape latency and traveled path to find t...