Increased expression of cellular membrane bound glucose-regulated protein 78 (GRP78) is considered to be one of the biomarkers for gastric cancers. Therefore, peptides or molecules with specific recognition to GRP78 can act as a guiding probe to direct conjugated imaging agents to localized cancers. Based on this rationale, GRP78-guided polymeric micelles were designed and manufactured for nucl...

This study investigates the relationship between variation due to prosodic prominence and variation due to sound change. We compare two hypotheses: under prominence vowels move in the direction of vowel shift, and under prominence vowels are hyperarticulated, and move to positions more peripheral in the vowel space. These hypotheses make competing predictions for two vowels currently undergoing...

Clustering based on similarity is one of the most important stages in data analysis and a beneficial tool for data mining. There are a wide range of data from which a clear pattern cannot be driven using common clustering methods, data with unusual shapes. Scientists introduced density-based clustering algorithms to resolve this issue and enable clustering for this kind of data. Among all densi...

The decision to include or exclude phonemes in the description of a language is not always straightforward; presentations phoneme inventory Modern Standard German (MSG) often discussion why /ɛ:/ problematic as phoneme. This study describes acoustic realization comparison /e:/ spoken German, specifically South Westphalian. 39 native speakers produced and hVt non-word frames vowel productions wer...

Abstract The pressure gradient term plays a vital role in convective heat transfer the boundary layer flow of Maxwell fluid over stretching sheet. importance effects can be monitored by developing Maxwell’s equation momentum and energy with term. To achieve this goal, an approximation technique, i.e. Homotopy Perturbation Method (HPM) is employed application algorithms Adams (AM) Gear (GM). Wit...