The theoretical description of the adsorption proteins at liquid/fluid interfaces suffers from inapplicability classical formalisms, which soundly calls for development more complicated models. A Frumkin-type thermodynamic 2-d solution model that accounts nonidealities interface enthalpy and entropy was proposed about two decades ago has been continuously developed in course comparisons with ex...

To answer challenge of targeted and controlled drug release in oral delivery various materials were studied by different methods. In the present paper, controlled metal based drug (Pd(II) complex) release manner of β‑Lactoglobulin (β-LG) nanoparticles was investigated using mathematical drug release model in order to design and production of a new oral drug delivery system for gastrointestinal ...

CHITIN NANOCRYSTAL STABILIZED EMULSIONS: STABILITY, INTERACTIONS WITH BETA-LACTOGLOBULIN, DIGESTION BEHAVIOR AND CYTOTOXICITY Chandni Chandran Advisor University of Guelph,2015 Dr Loong Tak Lim Solid particle stabilized emulsions have gained attention due to their surfactant free nature and high stability. However, insights on the interactions between solid particles stabilizing emulsions and s...

Cow milk is an important source of food protein for children, however, it could lead to allergy, especially infant. α-lactalbumin (α-LA) and β-lactoglobulin (β-LG) from whey make up a relatively high proportion proteins have received widespread attention as major allergens in milk. However, few studies identified the epitopes both simultaneously. In this study, ImmunoCAP indirect ELISA were fir...

cow’s milk allergy is one of the most common food allergies in childhood. beta- lactoglobulin (β-  lg) is  a dominant  allergen in  cow’s milk. hydrolysis is  known as  an effective method to reduce the allergenicity of proteins. thus, the objective of this study was to compare the allergenicity of β-lg and its hydrolysates using an animal model. twenty four balb/c mice were divided into three ...

Bovine β-lactoglobulin (β-lg), consisting of pronounced β-sheet content, have been chosen as a model protein which on prolonged thermal treatment forms large molecular aggregates similar to Alzheimer’s type amyloid fibrils. The effects of L-arginine (free base) in thermal aggregation process of β-lg were monitored at varying concentrations. Concentration dependent opposite behaviour has been re...