Glued mutations in Drosophila comprise an essential complementation group with complex developmental effects. The original Glued mutation (Gl) has dominant nonlethal effects in heterozygous flies, principally on the morphogenesis of the visual system. Gl also has a recessive lethal effect early in development. Mutations that reverse the dominant visual effects of Gl (GlR mutations) were induced...

The anaphase-promoting complex (APC) is a multisubunit E3 ubiquitin ligase that targets key cell cycle regulatory proteins for degradation. Blockade of APC activity causes mitotic arrest. Recent evidence suggests that the APC may have roles outside the cell cycle. Several studies indicate that ubiquitin plays an important role in regulating synaptic strength. We previously showed that ubiquitin...

This paper addresses the problem of detecting multidimensional subspace signals, which model range-spread targets, in noise unknown covariance. It is assumed that a primary channel measurements, possibly consisting signal plus noise, augmented with secondary measurements containing only noise. The noises these two channels share common covariance matrix, up to scale, may be known or unknown. va...

In this paper, two suboptimum detectors are proposed for coherent radar signal detection in K-distributed clutter. Assuming certain values for several initial moments of clutter amplitude, the characteristic function of the clutter amplitude is approximated by a limited series. Using the Pade approximation, it is then converted to a rational fraction. Thus, the pdf of the clutter amplitude is o...

Overcrowding in emergency departments (EDs) is a primary concern for hospital administration. They aim to efficiently manage patient demands and reducing stress the ED. Detection of abnormal ED (patient flows) systems aids managers obtain appropriate decisions by optimally allocating available resources following attendance. This paper presents monitoring strategy that provides an early alert w...

In 1952, Gelfand and Fomin noticed that classical modular forms were related to representations of SL2(R). As a result of this realization, Gelfand later defined GLr automorphic forms via representation theory. A metaplectic form is just an automorphic form defined on a cover of GLr, called a metaplectic group. In this talk, we will carefully construct the metaplectic covers of GL2(F) where F i...

Most SPC approaches for detecting the process variance assume that it remains constant over time. However, these approaches may not be well handled with the case in which patterned changes exist. In this paper, we propose a new control chart which integrates EWMA procedure with generalized likelihood ratio (GLR) test statistics for monitoring patterned variance shifts. It can be easily designed...

We propose a new evolution equation for the gluon density relevant for the region of small xB . It generalizes the GLR equation and allows deeper penetration in dense parton systems than the GLR equation does. This generalization consists of taking shadowing effects more comprehensively into account by including multigluon correlations, and allowing for an arbitrary initial gluon distribution i...

We propose an algorithm for simultaneously detecting and locating changepoints in a time series, and a framework for predicting the distribution of the next point in the series. The kernel of the algorithm is a system of equations that computes, for each index i, the probability that the last (most recent) change point occurred at i. We evaluate this algorithm by applying it to the change point...