In This Issue In This Issue Wnt separate ways, met later embers of the Wnt family of secreted signaling proteins control a wide range of developmental and pathological processes, with each Wnt protein signaling through either the " canonical " or " noncanonical " pathway. Two papers in this issue (and a Comment on page 753) now bring these two pathways together, showing that the noncanonical ca...

Twelve unipolar manics satisfying the inclusion criteria of having had three episodes of mania without a depressive episode were compared against bipolar manics on clinical psychopathology, demographic variables and family history of psychiatric morbidity. We Found no differences between the two groups on any of the variables studied and concluded that unipolar mania is clinically homogenous wi...

Four decades after the civil rights revolution began with the Supreme Court’s unanimous 1954 school desegregation decision, Brown v. Board of Education, the Supreme Court reversed itself in the 1990s, authorizing school districts to return to segregated and unequal public schools.... The new policies refl ected the victory of the conservative movement that altered the federal courts and turned ...

As code generation for synchronous programs requires strong safety properties to be satisfied, compositionality becomes a difficult goal to achieve. Most synchronous languages, such as Esterel, Lustre or Signal require a given module or compilation unit to be insensitive to latency that communication with its environment may incur. In Lustre or Signal, for instance, a compilation unit must sati...