The removal or repair of DNA damage has a key role in protecting the genome of the cell from the insults of cancer-causing agents. This was originally demonstrated in individuals with the rare genetic disease xeroderma pigmentosum, the paradigm of cancer genes, and subsequently in the relationship between mismatch repair and colon cancer. Recent re ports suggest that individuals with less drama...

Here, we describe a numerical method which combines a mixed nite volume//nite element formulation on unstructured triangulations and a linearized implicit method for time advancing. A particular attention has been paid to the source term implicitation. This method is applied to three typical low-Reynolds number k ? " models, namely those of Lam-Bremhorst, Nagano-Tagawa and Speziale-Abid-Anderso...

Este artigo é um recorte de uma pesquisa concluída que teve como objetivo investigar a materialidade creches públicas municipais Campina Grande, na Paraíba. O foco deste será o direito dos bebês e das professoras à disponibilidade materiais pedagógicos diversificados, adequados especificidade crianças, em número suficiente para todos/as tenham acesso às diferentes possibilidades educativas oriu...

Stochastic modeling is a exible method for handling the large variability in speech for recognition applications. In contrast to dynamic time warping where heuris-tic training methods for estimating word templates are used, stochastic modeling allows a probabilistic and automatic training for estimating models. This paper deals with the improvement of stochastic techniques, especially for a bet...

We present a model for a library of synchronous VLSI components, which describes both their function and their timing diagrams, without describing the internal implementation of the circuit. Our model is based on Synchronous Data Flow, with extentions to model VLSI circuits, and to verify that a system designed with VLSI components from our library is properly synchronized. Initialization and t...

In the present work, a novel computational framework for variational non-rigid image registration is discussed. The fundamental aim is to provide an alternative to approximate approaches based on successive convolution, which have gained great popularity in recent years, due to their linear complexity and ease of implementation. An optimise-then-discretise framework is considered. The correspon...

This report presents a novel representation model of parallel relational query execution plans, called DPL graphs. This model allows to deal with any kind of parallel architecture and any kind of parallel execution strategy. Based on an analysis of execution dependencies between operators, this model allows to precisely represent communications, run-time control mechanisms, scheduling constrain...