Aberrant profiles of pre-mRNA splicing are frequently observed in cancer. At the molecular level, an altered profile results from a complex interplay between chromatin modifications, the transcriptional elongation rate of RNA polymerase, and effective binding of the spliceosome to the generated transcripts. Key players in this interplay are regulatory splicing factors (SFs) that bind to gene-sp...

OBJECTIVE To determine the validity and reliability of the 13-figure images scale (13-CS) and Standard Figural Stimuli (SFS) for the evaluation of body images in adolescent students from Bucaramanga. METHODS A probabilistic sample with 189 students was evaluated with the two scales. Two weeks later, the valuation together with the size, weight, percentage of body fat, SCOFF questionnaire and ...

Designing the new microstructure is an effective way to accelerate the biomedical application of magnesium (Mg) alloys. In this study, a novel Mg-8Er-1Zn alloy with profuse nano-spaced basal plane stacking faults (SFs) was prepared by combined processes of direct-chill semi-continuous casting, heat-treatment and hot-extrusion. The formation of SFs made the alloy possess outstanding comprehensiv...

The recently described IL-33 acts as a pro-inflammatory cytokine, inducing the expression of multiple responses in the target cells. Although a nuclear localization of IL-33 has been described, its exact functional relevance is presently unknown. The present study was conducted to analyze the effects of IL-33 on the TNF-α induced synthesis of the ...

Since the dawn of nuclear physics (d,p) reactions have been the main tool to extract spectroscopic factors (SFs) (we call them phenomenological SFs), which were compared with predictions of the independent-particle shell model (ISPM). Later on electron-induced breakup reactions and nucleon knockout reactions became new tool to determine the SFs. Reduction of the phenomenological SFs deduced fro...

Received February 11, 1992; revised manuscript received July 24, 1992; accepted October 21, 1992 In previous research (Tech. Rep. 172, University of Southern California, Los Angeles, Calif., 1991) we developed an iterative shape-from-shading (SFS) algorithm that uses a single image, by combining a triangular-element surface model with a linearized reflectance map. In the current research we gen...

Orbital frontal cortex (OFC) is known to play a role in object recognition by generating "first-pass" hypotheses about the identity of naturalistic images based on low spatial frequency (SF) information. These hypotheses are evaluated by more detailed (and slower) ventral visual pathway processes. While it has been suggested on theoretical grounds, it remains unknown whether OFC also receives p...

Owing to increase in desired user throughput and to the subsequent increase in network traffic, the number and density of cells in cellular networks have increased, especially starting with LTE. This directly translates into higher capital and operational expenses as well as increased complexity of network operation. To counter all three challenges, Self-Organized Networks (SON) have been propo...

INTRODUCTION The Social Functioning Scale (SFS) was designed to evaluate social functioning essential to schizophrenic patients. Its length may be difficult to use in clinical practice. The objective of this study was to develop and validate a short version of the SFS. METHODS Data from 445 patients with schizophrenia who came from two separate studies, one longitudinal (n=250) and one cross-...

There is growing evidence that activated synovial fibroblasts, as part of a complex cellular network, play an important role in the pathogenesis of rheumatoid arthritis. In recent years, significant progress has been made in elucidating the specific features of these fibroblasts. It has been understood that although macrophage and lymphocyte secreted factors contribute to their activation, rheu...