Some cases of breast cancer are composed of clones of hormonal-independent growing cells, which do not respond to therapy. In the present study, the effect of Benzene-Poly-Carboxylic Acid Complex (BP-C1) on growth of human breast-cancer cells was tested. BP-C1 is a novel anti-cancer complex of benzene-poly-carboxylic acids with a very low concentration of cis-diammineplatinum (II) dichloride. H...

The teratocarcinoma-derived C1 clone behaves as a mesodermal tripotential progenitor cell whose choice of fate, either osteoblast, chondroblast, or adipoblast, is strictly dependent on the spatial organization of the cells and the nature of the induction. In the absence of cell contact before the addition of inducers, the C1 cells maintain a stable undifferentiated phenotype while expressing po...

BACKGROUND : Agents for prophylaxis of hereditary angioedema (HAE) have been available in the United States for several decades, but their usefulness is limited by side effects and they cannot be used at all in some patients. No agents have been available in the United States to specifically treat acute attacks. HAE types I and II are associated with low functional levels of C1 inhibitor, and e...

We make a detailed study of the three-body decays ${B}_{(s)}\ensuremath{\rightarrow}{\ensuremath{\chi}}_{c1}h{h}^{\ensuremath{'}}$, where ${h}^{{(}^{\ensuremath{'}})}$ is either pion or kaon, by taking into account $S$-wave states in $h{h}^{\ensuremath{'}}$ invariant mass distribution within perturbative QCD approach. The two meson amplitudes are introduced to capture strong interaction related...

A series of binary metal complexes (halo, hydroxyl and methoxy substituted bis(2-(E)acryloyl)naphthalen-1-yl)oxy)Cu(II) Zn(II) (C1? ?C10)) Cu2+ Zn2+ ions derived from bi-coordinated hydroxylated 1,3- -diaryl-2-propene-1-ones were synthesized. The newly synthesized structurally determined by FT-IR, 1H-NMR, 13C-NMR, ESR spectral, XRD TGA analyses. FT-IR studies demonstrated that interactions betw...

Activated high molecular weight Hageman factor (75 Kd) and Hageman factor carboxy-terminal fragments both formed complexes with purified C1(-)-inhibitor, but the Hageman factor fragments appeared to have a higher affinity for the C1(-)-inhibitor than activated Hageman factor. Therefore, the clot-promoting activity of activated Hageman factor might be relatively unimpaired if Hageman factor frag...

Seven Sungkai Peronemins compounds belong to the alkaloid group, Peronemin A2, A3, B1, B2, B3, C1, and D1. contains several bioactive compounds, triterpenoids, alkaloids, flavonoids, phenolics, steroids, saponins which can act as anti-inflammatory candidates. Geometry optimization find most stable molecular structure SMILES of peronemin compound was used predict pIC50 using pChEMBL® program. Fr...

background: hereditary angioedema (hae) is a rare autosomal dominant primary immunodeficiency with complement system defect characterized by recurrent episodes of angioedema involving the skin or mucosa of the upper respiratory and gastrointestinal tracts. objective: to characterize the clinical and laboratory data of hereditary angioedema in iran. methods: patients with probable diagnosis of a...

The initial processing of corneal sensory input in the rat occurs in two distinct regions of the spinal trigeminal nucleus, at the subnucleus interpolaris/caudalis transition (Vi/Vc) and in laminae I-II at the subnucleus caudalis/spinal cord transition (Vc/C1). Extracellular recording was used to compare the effects of morphine on the evoked activity of corneal-responsive neurons located in the...

This note considers the problem how zeros lying on the boundary of a domain influence the norm of polynomials (under the normalization that their value is fixed at a point). It is shown that k zeros raise the norm by a factor (1 + ck/n) (where n is the degree of the polynomial), while k excessive zeros on an arc compared to n times the equilibrium measure raise the norm by a factor exp(ck/n). T...