نتایج جستجو برای: روش ubc

تعداد نتایج: 370759  

2016
Claudia Berrondo Jonathan Flax Victor Kucherov Aisha Siebert Thomas Osinski Alex Rosenberg Christopher Fucile Samuel Richheimer Carla J. Beckham Javier S Castresana

Exosomes are 30-150nM membrane-bound secreted vesicles that are readily isolated from biological fluids such as urine (UEs). Exosomes contain proteins, micro RNA (miRNA), messenger RNA (mRNA), and long non-coding RNA (lncRNA) from their cells of origin. Although miRNA, protein and lncRNA have been isolated from serum as potential biomarkers for benign and malignant disease, it is unknown if lnc...

Journal: :The Journal of biological chemistry 2014
Wei Zhao Cunjie Chang Yangyan Cui Xiaozhi Zhao Jun Yang Lan Shen Ji Zhou Zhibo Hou Zhen Zhang Changxiao Ye Donald Hasenmayer Robert Perkins Xiaojing Huang Xin Yao Like Yu Ruimin Huang Dianzheng Zhang Hongqian Guo Jun Yan

Cancer cell proliferation is a metabolically demanding process, requiring high glycolysis, which is known as "Warburg effect," to support anabolic growth. Steroid receptor coactivator-3 (SRC-3), a steroid receptor coactivator, is overexpressed and/or amplified in multiple cancer types, including non-steroid targeted cancers, such as urinary bladder cancer (UBC). However, whether SRC-3 regulates...

2012
Sławomir Poletajew Maciej Walędziak Łukasz Fus Paweł Pomada Joanna Ciechańska Aleksander Wasiutyński

INTRODUCTION AND AIM Urothelial bladder carcinoma (UBC) is a very rare condition in patients aged below 50 years. The aim of the study was to answer the question whether the characteristics of cancer in this group of patients differ from general UBC features. MATERIAL AND METHODS Altogether 2160 patients treated with primary transurethral resection due to a bladder tumor were included in the ...

2016
Anne J. Grotenhuis Aleksandra M. Dudek Gerald W. Verhaegh Katja K. Aben J. Alfred Witjes Lambertus A. Kiemeney Sita H. Vermeulen

BACKGROUND Many studies investigated the prognostic or predictive relevance of single nucleotide polymorphisms (SNPs) in biologically plausible genes in urinary bladder cancer (UBC) patients. Most published SNP associations have never been replicated in independent patient series. OBJECTIVE To independently replicate all previously reported associations between germline SNPs and disease progn...

2009
Eneko Agirre Angel X. Chang Daniel Jurafsky Christopher D. Manning Valentin I. Spitkovsky Eric Yeh

This paper describes the joint Stanford-UBC knowledge base population system. We developed several entity linking systems based on frequencies of backlinks, training on contexts of anchors, overlap of context with the text of the entity in Wikipedia, and both heuristic and supervised combinations. Our combined systems performed better than the individual components, which situates our runs bett...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1996
A Aristarkhov E Eytan A Moghe A Admon A Hershko J V Ruderman

Ubiquitin-dependent proteolysis of the mitotic cyclins A and B is required for the completion of mitosis and entry into the next cell cycle. This process is catalyzed by the cyclosome, an approximately 22S particle that contains a cyclin-selective ubiquitin ligase activity, E3-C, that requires a cyclin-selective ubiquitin carrier protein (UBC) E2-C. Here we report the purification and cloning o...

Determining the ultimate bearing capacity (UBC) is vital for design of shallow foundations. Recently, soft computing methods (i.e. artificial neural networks and support vector machines) have been used for this purpose. In this paper, Random Forest (RF) is utilized as a tree-based ensemble classifier for predicting the UBC of shallow foundations on cohesionless soils. The inputs of model are wi...

Journal: :Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2014
Dimitra Grapsa Anna Dokou Vassiliki Tsokanou-Kouli Serafim Kaltsas Eleftheria Dalakou Rodoula Trigidou Muhammad W Saif Ekaterini Politi

PURPOSE To reevaluate the expression levels of p53, p63, c-myc, p21(WAF1/cip1) and p27(kip1) proteins and their potential association with standard clinicopathological parameters, including tumor stage and grade, in urothelial bladder carcinoma (UBC). METHODS Immunohistochemistry was performed in 100 transurethral resection specimens obtained from prospectively identified patients with primar...

2010
Angel X. Chang Valentin I. Spitkovsky Eric Yeh Christopher D. Manning Eneko Agirre

This paper describes the joint Stanford-UBC knowledge base population system for the entity linking task. We modified our 2009 approach, which was based on frequencies of Wikipedia back-links, providing a context-independent mapping from strings to possible Wikipedia titles. We then built on this foundation, taking into account named-entity recognition (NER) and coreference resolution informati...

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