Protein C inhibitor (PCI), which was originally identified as an inhibitor of activated protein C, also efficiently inhibits coagulation factors such as factor Xa and thrombin. Recently it was found, using purified proteins, that the anticoagulant thrombin-thrombomodulin complex was also inhibited by PCI. The paradoxical inhibitory effect of PCI on both coagulant and anticoagulant proteases rai...

chronic total occlusion (cto) intervention is still a challenging problem. the aim of this study is to determine factors that affect pci results.the study was conducted on 72 patients in two centers. cto angioplasty was done by the antegrade approach from the femoral and/or radial approach. the role of age, gender, anatomical variations such as calcification, length of the lesion, proximal bend...

the existence of ra 226 is proved and measured by radiom emanation-method in waters and food products of north , north west and north – east of iran. a total of 126 water, 249 food and 22 air samples have been examined. the concertration of ra 226 in waters found to be 0.01 to 1.104 pci/1 and in food products from 0.01 to pci/gr. ash.the amount found in due ranges from 0.003 to 0.227 pci/m 3.it...

OBJECTIVES This prespecified subgroup analysis examined the effect of diabetes on left main coronary disease (LM) and/or three-vessel disease (3VD) in patients treated with percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) in the SYNTAX trial. METHODS Patients (n = 1800) with LM and/or 3VD were randomized to receive either PCI with TAXUS Express paclitaxel-elu...

BACKGROUND Psychosocial stress and activation of neutrophil granulocytes are increasingly recognized as major risk factors of coronary artery disease (CAD), but the possible relationship of these two factors in CAD patients is largely unexplored. Activation of neutrophils was reported to be associated with stenting; however, the issue of neutrophil state in connection with percutaneous coronary...

BACKGROUND We aimed to assess the relationships of pentraxin-3 (PTX3) with coronary plaque components and myocardial perfusion after percutaneous coronary intervention (PCI) in order to clarify the mechanisms underlying the prognostic function of PTX3 in ST-elevation acute myocardial infarction (STEMI) patients. METHODS AND RESULTS We enrolled 75 STEMI patients who underwent pre-PCI virtual h...

BACKGROUND AND OBJECTIVES We investigated the effect of the additional use of abciximab during percutaneous coronary intervention (PCI) on the level of procoagulant microparticles (MPs) in patients with ST-segment elevation myocardial infarction (STEMI) who had undergone primary PCI. SUBJECTS AND METHODS In this study, we studied 86 patients with STEMI (72 men, age 58±13) who had undergone pr...

BACKGROUND The ultimate treatment goal for ST-segment elevation myocardial infarction (STEMI) is rapid reperfusion via primary percutaneous intervention (PCI). North Carolina has adopted a statewide STEMI referral strategy that advises paramedics to bypass local hospitals and transport STEMI patients directly to a PCI-capable hospital, even if a non-PCI-capable hospital is closer. METHODS AND...

OBJECTIVE We used optical coherence tomography (OCT) to assess the impact of thrombus aspiration before angioplasty on poststenting tissue protrusions in patients undergoing a primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI). METHODS AND RESULTS A total of 188 patients with STEMI who underwent thrombus-aspiration PCI (n=113) or standard P...

the existence of a high natural radiation area in the northern part of iran (ramsar) is proved. ra 226 in soil is measured. the results are: minimum 23.5 pci/g and maximum 999 pci/g soil. environmental radioactivity is from 0.1 to 5 mr/h.