AIM To study the coexistence of subthreshold diagnoses of both attention deficit hyperactivity disorder (ADHD) and disruptive behaviour disorders (DBD) with other symptoms of child and adolescent psychiatric disorders as well as risk behaviours associated with smoking, alcohol and drug use. METHODS A population-based sample of twins including 177 girls and 135 boys was interviewed using the S...

Methylphenidate remains the first choice treatment for attention deficit hyperactivity disorder (ADHD), but comorbid forms with Disruptive Behaviour Disorders (DBD) are undertreated. Methylphenidate adjunction is sometimes necessary in order to treat ADHD-related symptoms in DBD behaviors initially well-regulated with risperidone. In these situations, psychostimulant-antipsychotic combinations ...

The E1 protein from papillomaviruses is a multifunctional protein with complex functions required for the initiation of viral DNA replication. We have performed a surface mutagenesis of the well-characterized E1 DNA binding domain (DBD). We demonstrate that substitutions of multiple residues on the surface of the E1 DBD are defective for DNA replication without affecting the DNA binding activit...

This work reports the development of atmospheric pressure plasma reactor with dielectric barrier discharge DBD for material treatment. The DBD discharge has been generated in planar geometry reactor powered by ac voltage provided by conventional high voltage transformer. The dielectric barrier consisted of two glass slabs, which cover both reactor electrodes. The air discharge gap between the d...

Namdari P1, Nazari H2 1. Instructor, Department of Social Medicine, Faculty of Medicine, Lorestan University of Medical Sciences 2. Assistant Professor, Department of Psychiatry, Faculty of Medicine, Lorestan University of Medical Sciences, Iran Abstract Background: Disruptive Behavior Disorder (DBD) is one of the most prevalent psychiatric disorders starting from childhood and is co...

Solutions of ribose, glucose, and sucrose in water and phosphate buffer were treated with non-thermal plasma generated by using a dielectric barrier discharge (DBD) device and the oxidation products were characterized by H NMR and GC–MS. Our results demonstrate that these sugars are decomposed to formic acid, glycolic acid, glyceric acid, tartronic acid, tartaric acid, acetic acid, and oxalic a...

OBJECTIVES Outcomes of liver transplantations from donation after circulatory death (DCD) donors may be inferior to those achieved with donation after brain death (DBD) donors. The impact of using DCD donors is likely to depend on specific national practices. We compared risk-adjusted graft loss and recipient mortality after transplantation of DCD and DBD livers in the UK. DESIGN Prospective ...

Abstract Background and Aims The prevention/attenuation of graft ischemic injury is a challenge in kidney transplantation. We developed two rat models to investigate the impact mesenchymal stromal cells (MSCs) preconditioning kidneys from Donors after Circulatory Death (DCD) Brain (DBD). Method Under general anesthesia, rats underwent iv injection saline (S-groups) or 1.5 106 MSCs (MSC-groups) ...

BACKGROUND The nuclear receptor superfamily of transcription factors directs gene expression through DNA sequence-specific interactions with target genes. Nuclear import of these receptors involves recognition of a nuclear localization signal (NLS) by importins, which mediate translocation into the nucleus. Nuclear receptors lack a leucine-rich nuclear export signal (NES), and export is insensi...

OBJECTIVE Patterns of low autonomic arousal have consistently been related to delinquency and disruptive behavior disorders (DBD) in children and adolescents. Findings on another stress regulating mechanism, the hypothalamic pituitary adrenal (HPA) axis, have been inconsistent, which may partly be due to not considering specific stress reactivity measures. Therefore, the aim of the present stud...