BACKGROUND Pompe disease (acid α-glucosidase deficiency) is one of several lysosomal storage diseases amenable to treatment with enzyme replacement therapy (ERT). While echocardiography (echo) has been the standard method to evaluate the cardiac response to ERT, cardiac magnetic resonance imaging (CMR) has the advantage of a better tissue definition and characterization of myocardial fibrosis. ...

Abstract Background/Introduction Cardiac magnetic resonance imaging (CMR) is regarded as the reference method in assessing left ventricular (LV) myocardial mass. However, 2-dimensional echocardiography (Echo) still used due to availability and practicability. Purpose We sought assess measurements of LV mass from Echo exams validate results with CMR on a large cohort patients. Methods analyzed 3...

AIM This study was conducted to study the association between alcohol consumption and cardiovascular events and echocardiographical parameters in 100 consumers with the average daily dose <120 g and ≥120 g of alcohol per day during a 4-year follow-up. METHODS 100 patients/heavy alcohol consumers (on average ≥ 80 g daily), with no cardiovascular disease, divided into 2 groups, underwent a base...

OBJECTIVES Gating errors (GEs) with ECG gated myocardial SPECT (G-SPECT) may occur irrespective of the presence or absence of arrhythmias. We evaluated the impact of GEs on both reconstructed tomograms and left ventricular ejection fraction (LVEF) derived from G-SPECT, and searched for clues to identify these errors. METHODS We studied 2 GE patients, 10 normal subjects (NLs), and 10 atrial fi...