Centrosomes have many important functions and comprise a 'mother' and 'daughter' centriole surrounded by pericentriolar material (PCM). The mother centriole recruits and organises the PCM and templates the formation of the daughter centriole. It has been reported that several important Drosophila PCM-organising proteins are recruited to centrioles from the cytosol as part of large cytoplasmic '...

The electron transport through ultra-scaled amorphous phase change material (PCM) GeTe is investigated by using ab initio molecular dynamics, density functional theory, and non-equilibrium Green’s function, and the inelastic electron–phonon scattering is accounted for by using the Born approximation. It is shown that, in ultra-scaled PCM device with 6 nm channel length, <4 % of the energy carri...

تصویربرداری مقطع‌نگاری نوترونی یکی از کاربردهای مدرن رآکتورهای تحقیقاتی در سرتاسر جهان به‌شمار می‌رود. تلفیق قابلیت نمایش سه‌بعدی با ویژگی‌های منحصر به فرد برهم‌کنش نوترون مواد، می‌تواند اطلاعات بسیار ارزشمندی ساختار داخلی مواد و تجهیزات را اختیار محققین قرار ‌دهد. این تحقیق، تأثیر هندسه داده‌برداری تجربی روش بازسازی تصویر بر کیفیت تصاویر سامانه رآکتور تهران براساس شاخص وضوح میزان تولید نویز مو...

Background: Acetaminophen (Paracetamol; PCM), commonly utilized as analgesic and antipyretic drug in many painful and febrile disorders, has been found to induce liver and renal disorders in both animals and humans. Its administration in a high dose causes hepatic and renal toxicities and results in hepato-renal cell deaths by activating multiple stress pathways. Objective: This study aimed to ...

Photochemical machining (PCM), also known as photoetching, photofabrication or photochemical milling, is a non-traditional manufacturing method based on the combination of photoresist imaging and chemical etching. PCM uses techniques similar to those employed for the production of printed circuit boards and silicon integrated circuits. The PCM industry plays a valuable worldwide role in the pro...

BACKGROUND Naltrexone may improve success in primary care treatment of alcohol dependence (AD). This study tests naltrexone and primary care management (PCM) vs naltrexone and cognitive behavior therapy (CBT) and tests naltrexone maintenance among patients who respond to an initial course of naltrexone combined with PCM vs CBT. METHODS A nested sequence of 3 randomized trials was conducted. I...

The pericellular matrix (PCM) is the narrow tissue region surrounding all chondrocytes in articular cartilage and, together, the chondrocyte(s) and surrounding PCM have been termed the chondron. Previous theoretical and experimental studies suggest that the structure and properties of the PCM significantly influence the biomechanical environment at the microscopic scale of the chondrocytes with...

BACKGROUND Paracoccidioidomycosis (PCM) is one of the most important systemic mycoses in Latin America and the leading fungal cause of mortality in non-immunosuppressed individuals in Brazil. However, HIV/PCM co-infection can increase the clinical severity in these co-infected patients. This co-infection is rarely reported in the literature mainly because of the different epidemiological profil...

Background and study aims  Endoscopic submucosal dissection (ESD) is a technically advanced procedure for colorectal tumors. Hayashi et al. invented the "pocket-creation method (PCM)," and reported that Is-type lesions with fibrosis could be efficaciously and safely resected. However, only case studies have been published, and there are no previous reports on the usefulness of PCM in colorectal...