Congenital myasthenia gravis is caused by genetic mutations affecting neuromuscular transmission, characterized by muscle weakness usually starting in childhood. A two and a half years old male child presented with bilateral ptosis and hoarseness of voice. The symptoms progressed giving the clinical impression of congenital myasthenia gravis. A series of tests were done including Ice Pack Test,...

Myasthenia gravis is an autoimmune disease that results from an antibody-mediated reaction and occurs with thymoma in 15% of patients. It is very rarely associated with autoimmune hepatitis. Four cases of myasthenia gravis with autoimmune hepatitis have been reported in the world. We recently experienced a case of 30-year-old man with myasthenia gravis associated with thymoma and autoimmune hep...

objective this study was undertaken to evaluate the clinical spectrum of myasthenia gravis in children and determine factors that help the clinician in his/her diagnosis and management. materials & methods a retrospective review was performed on all pediatric patients suffering from myasthenia gravis (m.g) admitted in the department of pediatric neurology of the mofid hospital of the shaheed be...

A case of myasthenia gravis in a 15 years old girl is pre·sented. The disease was present for 5 years before thymectomy was performed. Indications for thymectomy, preoperative pre­paration, anesthetic and surgical management is -discussed. 

BACKGROUND In the investigation of patients with myasthenia gravis, repetitive supramaximal stimulation of an affected peripheral nerve is commonly performed to detect abnormal transmission at the neuromuscular junction. A study was undertaken to determine whether abnormal transmission could similarly be detected during stimulation of the phrenic nerves. METHODS The phrenic nerves were stimul...

[1] Sekine H, Kawaguchi N, Hamada C, Sekiguchi H, Yasufuku K, Iyoda A, Shibuya K, Fujisawa T. Does perioperative high-dose prednisolone have clinical benefits for generalized myasthenia gravis? Eur J Cardiothorac Surg 2006;29:908—13. [2] Endo S, Yamaguchi T, Saito Y, Otani S, Hasegawa T, Sato Y, Sohara Y. Experience with programmed steroid treatment with thymectomy in nonthymomatous myasthenia ...

Myasthenia gravis is a chronic autoimmune disease of neuromuscular transmission resulting in fatigable skeletal muscle weakness. Preeclampsia is a multisystem disease of pregnancy which is characterised by hypertension and involvement of one or more organ systems. Both diseases are responsible for considerable morbidity and mortality for mother and fetus. The occurrence of both preeclampsia and...

there are many tests for diagnosis of myasthenia gravis including tensilon test and ice test.to compare the ice test with tensilon test in sub jects with myasthenic and nonmyasthenic ptosis a process research study was designed. this study was performed in patients complaining of acquired ptosis in the neuro-ophthalmology center of farabi hospital. all 156 patients were tested with ice pack and...

Imiquimod activates the immune system when applied to a local area. We report a patient with a history of well-controlled myasthenia gravis who was prescribed imiquimod for lentigo maligna. Treatment was halted after 2 weeks when the patient reported itching and irritating sensations in his throat, consistent with previous myasthenia exacerbations. The symptoms improved once imiquimod use was d...