We (Wang H, Berschneider HM, Du J, and Black DD. Am J Physiol Gastrointest Liver Physiol 272: G935-G942, 1997; Wang H, Lu S, Du J, Yao Y, Berschneider HM, and Black DD. Am J Physiol Gastrointest Liver Physiol 280: G1137-G1144, 2001) previously showed that different fatty acids influence synthesis and secretion of triacylglycerol (TG) and phospholipid (PL) in a newborn swine enterocyte cell line...

BACKGROUND This study was designed to investigate the relation of a molecular analysis of apolipoprotein B (apoB)-containing atherogenic lipoprotein particles to coronary artery disease (CAD) in middle-aged men. METHODS AND RESULTS Two groups of men were studied. The first consisted of 97 patients with angiographically documented CAD (greater than 50% stenosis of at least one coronary artery)...

BACKGROUND African-Americans have higher HDL, less visceral adipose tissue (VAT) and lower triglyceride (TG) and apoCIII concentrations than whites, despite being more insulin-resistant. We studied in African-American and white women the influences of insulin resistance and VAT on the apoAI concentrations of two HDL subspecies, one that contains apoCIII that is associated with increased risk of...

Cui, LiBin, Norberta W. Schoene, Lei Zhu, Jessica C. Fanzo, Ali Alshatwi, and K. Y. Lei. Zinc depletion reduced Egr-1 and HNF-3 expression and apolipoprotein A-I promoter activity in Hep G2 cells. Am J Physiol Cell Physiol 283: C623–C630, 2002. First published April 24, 2002; 10.1152/ ajpcell.00308.2001.—We examined the influence of zinc status on expression of certain transcription factors inv...

BACKGROUND Insulin resistance is linked to dyslipidemia, characterized by a decrease in high density lipoproteins and an increase in low density lipoproteins. Thiazolidinediones (TZDs) are insulin-sensitizing agents used to improve glycemic control in patients with type 2 diabetes. Recently, the safety of certain TZD regimens has been questioned because of associated adverse effects on the plas...

High-density lipoproteins (HDL) are typically defined as lipoprotein particles with buoyant densities from 1.063 to 1.21 g/mL and having apolipoprotein AI (apoAI) as the major apolipoprotein species. It has become increasingly appreciated that the HDL population consists of a collection of particles with diverse sizes, structures, and composition and functional properties that are thought to in...

High-density lipoproteins (HDL) are typically defined as lipoprotein particles with buoyant densities from 1.063 to 1.21 g/mL and having apolipoprotein AI (apoAI) as the major apolipoprotein species. It has become increasingly appreciated that the HDL population consists of a collection of particles with diverse sizes, structures, and composition and functional properties that are thought to in...