نتایج جستجو برای: ژن ctx

تعداد نتایج: 19672  

Journal: :Antimicrobial agents and chemotherapy 2013
Nathalie Grall Laurent Massias Thu Thuy Nguyen Sakina Sayah-Jeanne Nicolas Ducrot Elisabeth Chachaty Jean de Gunzburg Antoine Andremont

Antibiotics excreted into the intestinal tract, such as broad-spectrum cephalosporins, disrupt the indigenous microflora, affect colonization resistance (CR), and promote intestinal colonization by resistant bacteria. We tested whether oral DAV131, a charcoal-based adsorbent, would prevent colonization by a cefotaxime (CTX)-resistant Klebsiella pneumoniae strain (PUG-2) in CTX-treated mice. Mic...

Journal: :iranian journal of public health 0
m mirzaee dept. of microbiology, faculty of medicine, shahed university, tehran, iran mr pourmand dept. of pathobiology, school public health, tehran university of medical sciences, iran m chitsaz dept. of microbiology, faculty of medicine, shahed university, tehran, iran s mansouri dept. of microbiology, faculty of medicine, shahed university, tehran, iran

background: organisms producing ctx-m-β-lactamase are emerging around the world as a source of resistance to oxyiminocephalosporins such as cefotaxime. however, the laboratory detection of these strains is not well defined. the aim of this study was to determine the presence and prevalence of known ctx-m-β-lactamases genes in clinical isolates of  escherichia coli from hospitals of tehran. meth...

2011
Atupele Kapito-Tembo Steven R. Meshnick Michaël Boele van Hensbroek Kamija Phiri Margaret Fitzgerald Victor Mwapasa

BACKGROUND Effectiveness of cotrimoxazole (CTX) compared with sulfadoxine-pyrimethamine (SP) intermittent-preventive-therapy (IPTp) for malaria in HIV-infected pregnant women is unknown. We examined effectiveness of CTX with or without SP-IPTp versus SP-IPTp at reducing malaria parasitemia and anemia. METHODS From 2005 to 2009, we conducted a cross-sectional study of HIV-infected pregnant wom...

Journal: :Stroke 2007
Kon Chu Soon-Tae Lee Dong-In Sinn Song-Yi Ko Eun-Hee Kim Jeong-Min Kim Se-Jeong Kim Dong-Kyu Park Keun-Hwa Jung Eun-Cheol Song Sang Kun Lee Manho Kim Jae-Kyu Roh

BACKGROUND AND PURPOSE Astrocytic glutamate transporter protein, GLT-1 (EAAT2), recovers extracellular glutamate and ensures that neurons are protected from excess stimulation. Recently, beta-lactam antibiotics, like ceftriaxone (CTX), were reported to induce the upregulation of GLT-1. Here, we investigated ischemic tolerance induction by CTX in an experimental model of focal cerebral ischemia....

2013
Hisakazu Yano Mina Uemura Shiro Endo Hajime Kanamori Shinya Inomata Risako Kakuta Sadahiro Ichimura Miho Ogawa Masahiro Shimojima Noriomi Ishibashi Tetsuji Aoyagi Masumitsu Hatta Yoshiaki Gu Mitsuhiro Yamada Koichi Tokuda Hiroyuki Kunishima Miho Kitagawa Yoichi Hirakata Mitsuo Kaku

The prevalence of ESBL has been increasing worldwide. In this study, we investigated the molecular characteristics of ESBL among clinical isolates of Escherichia coli from a Japanese tertiary hospital. A total of 71 consecutive and nonduplicate clinical isolates of ESBL-positive E. coli collected at Tohoku University Hospital between January 2008 and March 2011 were studied. The antimicrobial s...

2013
GUANGZHU LIN XIAOFENG YU JING WANG SHAOCHUN QU DAYUAN SUI

20(S)-protopanaxadiol (PPD) is an extract of Panax quinquefolius L. The aim of this study was to investigate the effect of PPD on the antitumor activity and toxicity of cyclophosphamide (CTX) in tumor-bearing mice. C57BL/6 mice bearing Lewis lung carcinoma cells were treated with PPD (50 mg/kg) alone, CTX (20 mg/kg) alone or PPD (50 mg/kg) in combination with CTX (20 mg/kg), respectively. The r...

2014
Christine Manyando Eric M. Njunju David Mwakazanga Gershom Chongwe Rhoda Mkandawire Davies Champo Modest Mulenga Maaike De Crop Yves Claeys Raffaella M. Ravinetto Chantal van Overmeir Umberto D’ Alessandro Jean-Pierre Van geertruyden

INTRODUCTION Antibiotic therapy during pregnancy may be beneficial and impacts positively on the reduction of adverse pregnancy outcomes. No studies have been done so far on the effects of daily Co-trimoxazole (CTX) prophylaxis on birth outcomes. A phase 3b randomized trial was conducted to establish that daily CTX in pregnancy is not inferior to SP intermittent preventive treatment (IPT) in re...

Laleh Babaeekhou Leila Ahmadkhan Beygi Maryam Ghane,

Background: Production of β–lactamases by enterobacteriacea, especially Klebsiella pneumoniae, is one of the emerging health problems in the world. The purpose of this study was to assess the frequency of blaCTX-M15 gene in K. pneumoniae isolates and determine the molecular diversity of CTXM producing isolates. Methods: In...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2000
S L Kopka L C Geran A C Spector

We tested whether the recovered ability of rats to discriminate NaCl from KCl after chorda tympani nerve transection (CTX) is causally linked to nerve regeneration or some other compensatory process. Rats were presurgically trained in an operant NaCl vs. KCl discrimination task. Rats with regenerated nerves, histologically confirmed by anterior tongue taste pore counts and tested 62 days after ...

2013
Christine Manyando Eric M. Njunju Umberto D’Alessandro Jean-Pierre Van geertruyden

INTRODUCTION Cotrimoxazole (CTX) has been used for half a century. It is inexpensive hence the reason for its almost universal availability and wide clinical spectrum of use. In the last decade, CTX was used for prophylaxis of opportunistic infections in HIV infected people. It also had an impact on the malaria risk in this specific group. OBJECTIVE We performed a systematic review to explore...

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