A study was conducted during Zaid 2005, in Uttar Pradesh, India, to evaluate the nature and magnitude of genetic divergence in 30 bitter gourd genotypes. Results revealed the presence of wide genetic diversity. The genotypes were grouped into 6 clusters based on Mahalanobis D statistics using Tocher's 2 method. The clustering pattern of genotypes revealed that the genetic diversity was independ...

The association constants for the binding of a series of ligands with a galactose-specific lectin from Momordica charantia (bitter gourd) has been determined through the ligand-induced quenching of protein fluorescence. Analysis of the iodide quenching suggested that there is a slight increase in the accessibility of tryptophan residues of the lectin on binding lactose.

Acetone extract of whole fruit powder of Momordica charantia a given orally daily lowered the blood sugar and serum cholesterol levels to normal range after 15 to 30 days in alloxan diabetic rats. The blood sugar once lowered after 30 days treatment did not increase even after 15 days of discontinuation of the treatment.

Diabetes mellitus is a metabolic disorder in the endocrine system. This dreadful disease is found in all parts of the world and is becoming a serious threat to mankind health. There are lots of chemical agents available to control and to treat diabetic patients, but total recovery from diabetes has not been reported up to this date. Alternative to these synthetic agents, plants provide a potent...

BACKGROUND/OBJECTIVES The present study was conducted to investigate the effects of dried Momordica charantia aqueous extracts (MCA) and ethanol extracts (MCE) on obesity and lipid profiles in mice fed a high-fat diet. MATERIALS/METHODS Forty two ICR mice were randomly divided into six groups. The normal group was fed a basal diet, and other groups were fed a 45% high-fat diet (HFD) for 7 wee...

© 2013 Limtrakul et al., licensee InTech. This is an open access chapter distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Kuguacin J, a Triterpenoid from Momordica charantia Linn: A Comprehensive Review o...

The mechanism of action of the antidiabetic capacity of Momordica charantia is still under investigation. Here, we assessed phytochemical compositions, antioxidant activity, and effects of total and filtered fruit and leafy stem juices of Momordica charantia on human T cell proliferation and differentiation through quantification of Th1/Th2 cytokines. In the absence of stimulation, total fruit ...

Momordica charantia is a well known medicinal plant used in the traditional medicinal system for the treatment of various diseases including diabetes mellitus. Recently, a novel protein termed as ADMc1 from the seed extract of M. charantia has been identified and isolated showing significant antihyperglycemic activity in type 1 diabetic rats in which diabetes was induced. However, the structure...