OBJECTIVES The purpose of this study was to clarify characteristics of truncus arteriosus communis associated with chromosome 22q11 deletion (del 22q11). BACKGROUND DiGeorge syndrome and conotruncal anomaly face syndrome are associated with del 22q11 (hemizygosity). In 30% of cases, truncus arteriosus communis is associated with the deletion. METHODS Fifteen consecutive patients with truncu...

The human reduced folate carrier (hRFC) is reported to be regulated by up to seven alternatively spliced noncoding exons (A1, A2, A, B, C, D, and E). Noncoding exon and promoter usage was analyzed in RNAs from 27 childhood acute lymphoblastic leukemia (ALL) specimens by real-time PCR and/or 5' rapid amplification of cDNA ends (5' RACE) assay. By real-time PCR, total hRFC transcripts in ALL span...

A subset of male germ line-specific genes, the MAGE-type genes, are activated in many human tumors, where they produce tumor-specific antigens recognized by cytolytic T lymphocytes. Previous studies on gene MAGE-A1 indicated that transcription factors regulating its expression are present in all tumor cell lines whether or not they express the gene. The analysis of two CpG sites located in the ...

Both A1 and A2 mating types of Phytophthora infestans were detected in El-Behera governorate and the surrounding area where potato and tomato were intensively cultivated during the 2005-2006 growing season. The A2 mating type constituted 14.8% of the total isolates recovered (162) while A1 mating type constituted 83.9%. A 7.4% of the total potato and tomato fields (94) surveyed yielded A2 matin...

A variety V has tolerances permutable with factor congruences if for any A1, A2 of V and every tolerance T on A1 × A2 we have T ◦ Π1 = Π1 ◦ T and T ◦ Π2 = Π2 ◦ T , where Π1,Π2 are factor congruences. If B is a subalgebra of A1×A2, the congruences Θi = Πi∩B are called decomposing congruences. V has tolerances permutable with decomposing congruences if T ◦ Θi = Θi ◦ T (i = 1, 2) for each A1, A2 ∈...