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Affiliations: 5 Population Biology Laboratory, Biology Division, Indian Institute of Science Education and 6 Research-Pune, Dr. Homi Bhabha Road, Pune, India, 411 008 7 8 Evolutionary Biology Laboratory, Evolutionary and Organismal Biology Unit, Jawaharlal 9 Nehru Centre for Advanced Scientific Research, Jakkur P.O., Bengaluru, India, 560 064 10 Present Address: Clintus Network Ltd., No. 205/1 ...
The gastroesophageal reflux presence in asthma has been the subject of many studies indicating their frequent coexisting. The essence of this correlation is not entirely clear and several hypotheses can be found in literature. Recently defined laryngopharyngeal reflux and studies on its impact on the course of asthma seem to bring us closer to understanding this issue. In the last years we gain...
We propose here the application of synaptic vesicle proteins isolated from rat brain as a sole substrate for the specific endoproteinase activities of all seven serotypes of Botulinum Neurotoxin (BoNT/A to G). In this study, we used these proteins for evaluating endopeptidase and receptor binding activity for detecting BoNT/A by western blot and surface plasmon resonance with 6.25 pM and 0.22 f...
Affiliations: 6 Population Biology Laboratory, Biology Division, Indian Institute of Science Education and 7 Research-Pune, Dr. Homi Bhabha Road, Pune, India, 411 008 8 9 Evolutionary Biology Laboratory, Evolutionary and Organismal Biology Unit, Jawaharlal 10 Nehru Centre for Advanced Scientific Research, Jakkur P.O., Bengaluru, India, 560 064 11 Present Address: Clintus Network Ltd., No. 205/1...
A prophylactic vaccine is needed to slow the spread of HIV-1 infection. Optimization of the wild-type envelope glycoproteins to create immunogens that can elicit effective neutralizing antibodies is a high priority. Starting with ten genes encoding subtype B HIV-1 gp120 envelope glycoproteins and using in vitro homologous DNA recombination, we created chimeric gp120 variants that were screened ...
BackgroundMultiple sclerosis (MS) poses a major threat to sustainable employability. Identifying conditions and factors that promote work participation is of great importance. Our objective was explore the contribution personality traits in explaining occupational functioning MS.Methods241 participants with relapsing-remitting MS (78% female, median age: 42.0 years, EDSS: 2.0) 60 healthy contro...
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