PURPOSE Given the neurocognitive toxicity associated with whole-brain irradiation (WBRT), approaches to defer or avoid WBRT after surgical resection of brain metastases are desirable. Our initial experience with stereotactic radiosurgery (SRS) targeting the resection cavity showed promising results. We examined the outcomes of postoperative resection cavity SRS to determine the effect of adding...

OBJECTIVE To evaluate feasibility, efficacy, and tolerability of Sudarshan Kriya yoga (SKY) as an adjunctive intervention in patients with major depressive disorder (MDD) with inadequate response to antidepressant treatment. METHODS Patients with MDD (defined by DSM-IV-TR) who were depressed despite ≥ 8 weeks of antidepressant treatment were randomized to SKY or a waitlist control (delayed yo...

We report on a multiwavelength campaign on the TeV γ-ray blazar Markarian (Mrk) 421 performed during December 2002 and January 2003. These target of opportunity observations were initiated by the detection of X-ray and TeV Department of Physics, Washington University, St. Louis, MO 63130, USA Physics Department, Tanta University, Tanta, Egypt Department of Physics, University of Massachussetts,...

Intervention studies have demonstrated that saturated fat increases total and LDL-cholesterol concentrations, and it is therefore recommended that the intake of high-fat dairy products be limited. However, observational studies have found an inverse relationship between the intake of dairy products and incidence of CVD. We aimed to study whether the Ca content of dairy products influences the e...

BACKGROUND Cilostazol has reduced restenosis and repeat intervention after drug-eluting stent (DES) implantation. However, there is little data regarding impact of cilostazol on cardiac events after DES implantation. Therefore, we assessed the long-term efficacy and safety of cilostazol in patients undergoing successful DES implantation. METHODS The patients (n = 3,099) undergoing successful ...

PURPOSE Primary CNS lymphoma (PCNSL) is an aggressive lymphoma but clinically validated biologic markers that can predict natural history to tailor treatment according to risk are lacking. Several genetic changes including BCL6 rearrangements and deletion of 6q22, containing the putative tumor suppressor gene PTPRK, are potential risk predictors. Herein we determined the prevalence and survival...

This paper describes an original system, Orccad, for the computer-aided design of robot controllers. Accessed by three diierent user levels (system, control and application), it proposes a coherent approach from a high level speciication down to its implementation, and ooers several tools for design, display and test. Following a critical study of the main architectures reported through the lit...

Recent work has emphasized the importance of evaluating forecasts of a statistical functional (such as a mean, quantile, or distribution) using a loss function that is consistent for the functional of interest, of which there are an in…nite number. If forecasters all use correctly speci…ed models free from estimation error, and if the information sets of competing forecasters are nested, then t...

Entertainment and travel costs (ETC) is a standard expenditure item for Chinese …rms with an annual amount equal to about 3 percent of total value added. We use this objective accounting measure as a basis to analyze the composition of ETC and the e¤ect of ETC on …rm performance. Relying on the predictions from a simple model of managerial decision-making, we identify components of ETC by exami...