Variation in pharmacology and function of ligands at species orthologs can be a confounding feature in understanding the biology and role of poorly characterized receptors. Substantial selectivity in potency of a number of GPR35 agonists has previously been demonstrated between human and rat orthologs of this G protein-coupled receptor. Via a bioluminescence resonance energy transfer-based assa...

and lines of rhymed prose make it his longest work. *Ḥanukka-nāma (The Book of Hanukah), his other long narrative, is an account of the Maccabees’ successful military campaign against the Seleucid dynasty in the second century B.C.E. The extant manuscript copies are incomplete; in the introduction, however, Ben Samuel expresses his desire to continue in the tradition, begun by *Shāhīn in the fo...

This paper overviews the present status on therapy of regenerative medicine which is based on tissue engineering. Tissue engineering is a biomedical form which enables cells to promote their proliferation and differentiation, resulting in induction of tissue regeneration. The scaffold of 3-dimensional porous material for cells with or without the controlled release system of growth factor is ap...

The fur seal (Callorhinus ursinus) population has decreased in their primary breeding grounds in the Bering Sea; contamination is among suspected causes. Our goal was to better understand the extent of contamination of seal tissues with certain organochlorine compounds by measuring the concentrations of polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) in fur seal tissues fr...

Observability of Switched Linear Systems . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . D. Gómez-Gutiérrez, G. Ramírez-Prado, A. Ramírez-Treviño, and J. Ruiz-León 127 On Formal Analy...

The American Associationi for the Advancecnient of Scitintific Apparatus and Laboratory Methods: Science: The Demonstration. of Nervonts Syste ins by M1accrThle Stiultuts-Nenral Control of Behavior During ation of Whlole An1im1als: WILLIAM S. CORNWELL. and After Learnin?g: PROFESSOR WALTER S. Tlhe Absorptiont of Methyleene Blue by the NeltiiiNTER 145 phlridlinne7 of thle Earthlworme: PROFESSOR ...

Abstract Introduction Patients with chronic pain often experience poor sleep. Research demonstrating the bidirectional nature of pain/sleep association has focused on interindividual patterns based between person averages, leaving acute, intraindividual night-to-night fluctuations understudied. Because both and sleep fluctuate considerably, better understanding those may provide important insig...