Tetraphenylporphyrin aluminum(iii) salts, TPPAlX, where X = Me, OEt, OiPr, OCHMeCH2Cl, and Cl, and bis(triphenylphosphine)imminium chloride, PPN+Cl- (1 : 1) react with rac-lactide, rac-LA, in neat propylene oxide, PO, to yield chains of enriched isotactic polylactide, PLA, with end groups of PO-Cl and with time these yield cyclic polymers (PO)n(PLA) where n = 2 or 3 and even higher. There is no...

BACKGROUND We previously reported that σ1-receptor (σ1R) expression in the thoracic aorta decreased after pressure overload (PO) induced by abdominal aortic banding in ovariectomized (OVX) rats. Here, we asked whether stimulation of σ1R with the selective agonist SA4503 elicits functional recovery of aortic vasodilation and constriction following vascular injury in OVX rats with PO. METHODS A...

Kiessoun Konate*, Jacques Francois Mavoungou , Maurice Ouédraogo , Alexis Nicaise Lepengue , Alain Souza , Nicolas Barro 6 and Bertrand M’Batchi 1, 4 Laboratory of Animal Physiology, Electrophysiology and Pharmacology , Faculty of Sciences, University of Science and Technology of Masuku, PO Box: 943 Franceville, Gabon. Institute Research in Tropical Ecology . PO Box: 13354 Libreville Gabon Labo...

objective(s)cpg oligodeoxynucleotides (cpg odns) have been shown to have potent immunostimulatory adjuvant activity for a wide range of antigens. due to susceptibility of phosphodiester cpg odns (po cpg) to nuclease degradation, nuclease-resistant phosphorothioate cpg odns (ps cpg) were currently utilized in an in vivo model. in this study, according to some recently reported drawbacks with ps ...

BACKGROUND Canada has featured the second-highest levels of prescription opioid (PO) use globally behind the United States, and reported extensive PO-related harms (e.g., non-medical PO use [NMPOU], PO-related morbidity and mortality). A recent comprehensive review synthesized key data on PO use, PO-related harms, and interventions in Canada, yet a substantive extent of new studies and data hav...

J.M. Ojango N. Mpofu 1 4 K. Marshall and L. Andersson-Eklund International Livestock Research Institute (ILRI), PO Box 30709, Nairobi 00100, Kenya Swedish University of Agricultural Sciences (SLU), Dept. of Animal Breeding and Genetics, PO Box 7023, SE-75007 Uppsala, Sweden (sections 1.4 and 6) Egerton University, Department of Animal Sciences, PO Box 536, Njoro, Kenya Lupane State University, ...

Pioglitazone belongs to the thiazolidinedione (TZD) class of antidiabetic agents, with proven efficacy in increasing insulin sensitivity and in the treatment of type 2 diabetes mellitus in humans. Pioglitazone has been proposed as a potential feed additive to reduce insulin resistance and consequently some of the metabolic disorders in transition cows. This study was aimed at determining the ph...

For many neurons, N-type calcium channels provide the primary pathway for calcium influx during an action potential. We investigated the gating properties of single N-type calcium channels using the cell-attached patch technique. With 100 mM Ba2+ in the pipet, mean N-channel open probability (Po, measured over 100 ms) increased with depolarization, but the range at a single voltage was large (e...

The basis for the new procedure is the simultaneous transcutaneous measurement of the peri-ulceral oxygen partial pressure (tcPO(2)), using a minimum of 4 electrodes which are placed as close to the wound margin as possible, additionally, as a challenge the patient inhales pure oxygen for approximately 15 minutes. In order to evaluate the measurement data and to characterise the wounds, two new...

This exposition explains the basic ideas of Stein’s method for Poisson random variable approximation and Poisson process approximation from the point of view of the immigration-death process and Palm theory. The latter approach also enables us to define local dependence of point processes [Chen and Xia (2004)] and use it to study Poisson process approximation for locally dependent point process...