Phytochemical investigation of the rhizomes and roots of Ligularia veitchiana afforded a new triterpenoid saponin and two known neolignans named liguveitoside B (1), citrusin A (2) and citrusin B (3), respectively. This is the first demonstration of the occurrence of a 8-O-4’ neolignan and the second report on the isolation of triterpenoid saponin in the genus Ligularia. Their structures were e...

Daun nangka dan rempah-rempah seperti kapulaga, cengkeh, pekak diketahui memiliki kandungan antioksidan berupa tanin, saponin flavonoid. Tanin merupakan senyawa sekaligus yang menjadi ciri khas rasa sepat pada teh. Pemanfaatan daun rempah diolah teh herbal diharapkan mampu produk kaya antioksidan. Penelitian ini dilakukan untuk menganalisis dengan perbandingan dibanding 5:3, 6:2 7:1 terhadap, k...

Intramammary infections in cattle resulting in mastitis have detrimental effects on cows' well-being, lifespan and milk production. In the host defense against S. aureus mastitis antibodies are thought to play an important role. To explore potential ways to increase antibody titers in the bovine mammary gland the effects of various adjuvants on the magnitude, isotype, and neutralizing capacity ...

Secretory proteins migrate from the rough endoplasmic reticulum (ER) to the Golgi complex at different rates. Selective retention of specific proteins to rough-ER membrane constituents could explain this phenomenon. We have permeabilized HepG2 cells with low concentrations of saponin. Release of newly synthesized proteins was studied after brief labelling in the presence of [35S]methionine. The...

The incorporation of lucerne meal in the diet of chicks prevents normal gains in weight (Alder, 1946; Draper, 1948; Cooney, Butts & Bacon, 1948; Lepkovsky, Shaeleff, Peterson & Perry, 1950; Heywang, 1950; Kodras, Cooney & Butts, 1951 a, b). This effect is attributed to the saponin fraction of lucerne (Peterson, 195oa, b; Heywang & Bird, 1954), which has been shown to be a complex mixture of rel...

BACKGROUND Malignant melanoma is a highly aggressive malignant melanocytic neoplasm which resists against the most conventional therapies. Sea cucumber as one of marine organisms contains bioactive compounds such as polysaccharide, terpenoid and other metabolites which have anti-cancer, anti-tumor, anti-inflammatory and antioxidant properties. The present study was designed to investigate the a...