The RNA binding protein CELF1 (also known as CUGBP1) is emerging as a critical regulator of cancer cell proliferation and apoptosis. Here, to provide a global prospective of CELF1 regulation of oral squamous cell carcinoma, we performed RNA-sequencing in oral cancer cells and CELF1 overexpression analysis in non-malignant human oral keratinocytes. Our approaches identified 1283 mRNAs differenti...

We present a simple method for diode laser frequency stabilization that makes use of a Doppler-broadened vapor cell absorption signals of two frequency-shifted laser beams. Using second-order-diffracted, double-passed beams from an acousto-optic modulator, we achieve a frequency separation roughly equal to the Doppler half width. The differential transmission signals of the two beams provide an...

background: this study aimes to evaluate the failure to thrive (ftt) recurrent event over time. methods: this longitudinal study was conducted during february 2007 to july 2009. the primary outcome was growth failure. the analysis was done using 1283 children who had experienced ftt several times, based on recurrent events analysis. results: fifty-nine percent of the children had experienced th...

The paper presents the effects of blend injection and dual strategies on mixture formation combustion syngas-biogas-hydrogen fueling engine working in solar-biomass hybrid renewable energy system. research was performed by simulation method a retrofitted Honda GX200 spark-ignition engine. results show that at end compression process, case 50% syngas-50% biogas, fuel-rich zone positioned top cha...

В статье приводится информация о редких и ранее неопубликованных монетах Булгарского региона. Основное отличие – публикуемые экземпляры являются фракциями более крупных типов дирхамов. Всего приводятся 9 серебряных монет. Опираясь на монографию А.З. Сингатуллиной, авторы изучают метрологию фракций их аналогов. Все приведённые входят в систему номиналов, основанную минимальной единице данге 0,31...

Kallmann syndrome (KS) is characterized by hypogonadotropic hypogonadism and inability to smell (anosmia), owing to impaired targeting and migration of olfactory axons and gonadotropin-releasing hormone (GnRH)-secreting neurons (Kallmann, 1944). During normal development, olfactory neurons project their axons through the cribriform plate and the meningeal tissue and enter the olfactory bulb. Gn...