Anthracycline antibiotics like doxorubicin (DOX) are known to exert their antitumor effects primarily via DNA intercalation and topoisomerase II inhibition. By contrast, the noncross-resistant cytoplasmically localizing DOX analogue, N-benzyladriamycin-14valerate (AD 198), only weakly binds DNA and does not inhibit topoisomerase II, yet it displays superior antitumor activity, strongly suggesti...

In this research, the removal of Reactive Red 198 dye (RR-198) by Cuttlefish bone powder was investigated. The adsorbent was prepared in laboratory conditions and ground by ASTM standard sieves (60-100 mesh). The progress of the process is monitored spectrophotometrically by measuring the absorbance of dye at 518 nm wavelength. In addition, the effects of process parameter...

There are reports of early evidence that suggest the involvement of chronic low-grade inflammation in the pathogenesis of Type 2 diabetes. Thus, substances that have effects in reducing inflammation could be potential drugs for Type 2 diabetes. Leonurine (4-guanidino-n-butyl syringate; SCM-198) is an alkaloid in HL (Herba leonuri), which was reported to possess anti-inflammatory properties. We ...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Kopacz D, Czarny-Działak M. Cosmetology students’ knowledge about vitiligo. Medical Studies/Studia Medyczne. 2022;38(3):190-198. doi:10.5114/ms.2022.119917. APA Kopacz, D., & Czarny-Działak, (2022). Medyczne, 38(3), 190-198. https://doi.org/10.5114/ms.2022.119917 Chicago Daria, and Małgorzata A. Czarny-Działak. 20...

PURPOSE To investigate the clinicopathological value and potential roles of microRNA-198 (miR-198) in hepatocellular carcinoma (HCC). METHODS Ninety-five formalin-fixed paraffin-embedded HCC and the para-cancerous liver tissues were gathered. Real-time reverse transcription quantitative polymerase chain reaction was applied to determine the miR-198 expression. The association between the miR-...

this experiment was carried out the aim of the effect of sainfoin forage and forage:concentrate ratios on feed intake, nitrogen balance,ruminal biohydrogenation and milk fatty acid profile in dairy ewes using of eight lori breed ewes according to a replicated 4 × 4 latin square design. treatments were adjusted from one to four according to forage:concentrate ratios of 35:65 with and without sai...