The general and systemic physical examination was within normal limit. On local examination, there was a violaceous spot on the lunula and longitudinal ridging on the nail plate [Figure 1a]. The love test (applying pressure to the suspected area with a pinhead, which elicits exquisite localised pain) was positive. The posterior‐anterior and lateral view of X‐ray left hand was normal [Figure 1c]...

A 64-year-old man presented with a four-day history of intermittent abdominal pain and melaena. The patient had no past history of cancer and no family history of colorectal cancer. Physical examination revealed mild periumbilical and right lower quadrant abdominal tenderness without rebound tenderness. Laboratory examination showed no abnormality. Contrast-enhanced computed tomography (CT) (fi...

We describe a method for tying a self-locking knot to apply tension to a free tendon end for hamstring graft anterior cruciate ligament reconstruction. This is faster, safer and easier than Whip stitching and is secure enough to feed the graft through bone tunnels. The suture is folded and the tendon is laid on top (Fig 1a). The suture ends are then fed over the tendon and through the loop (Fig...

Using NC-AFM with CO terminated tips, atomic resolution on molecules has been demonstrated and the contrast mechanism was assigned to the Pauli repulsion [2] (see Fig.1c) . On the other hand, by using STM and by decoupling the molecules from the metallic substrate by an ultrathin insulating film, the molecular frontier orbitals, i.e. the highest occupied and the lowest unoccupied molecular orbi...

The syntheses and biological activities of new 7-beta-[(Z)-2-(2-amino-4-thiazolyl)-2-hydroxy-iminoacetamido]-3-(1 ,3- dithiolan-2-yl)-3-cephem-4-carboxylic acid (YM-22508, 1a), 7-beta-[(Z)-2-(2-amino-4-thiazolyl)-2- methoxyiminoacetamido]-3-(1,3-dithiolan-2-yl)-3-cephem-4-carboxyli c acid (YM-16457, 1d) and their prodrug-type esters are described. Among them, YM-22561 (1c), the 1-acetoxyethyl e...

coronal imaging; figure 1C). She was treated with osteosynthesis (figure 1D) to stabilise the femoral neck fracture, which resulted in a good functional outcome at 6-month follow-up. Occult femoral neck fractures are frequently misdiagnosed. Once misdiagnosed, the non-displaced fracture may become displaced. When this occurs, patients may need to be treated with hip arthroplasty, which is more ...

Francez and Berg (1994) introduced the term CROSS-SPEAKER ANAPHORA to indicate reference by conversational participant (CP) B to a discourse entity introduced by CP A. Crossspeaker anaphora is further discussed in (Groenendijk, Stokhof, and Veltman, 1997; Dekker, 1997), where it is noted that the phenomenon is subject to a number of constraints: e.g., it is generally not felicitous for B to fol...

A 66-year-old woman with hypertension and systemic lupus erythematosus presented with intermittent interscapular and chest pain, progressive dyspnea and presyncope episodes since the previous week. On physical examination she was hemodynamically stable, but jugular venous distension and diminished cardiac sounds were detected. Transthoracic echocardiography showed a pseudoaneurysm of the ascend...

from the right atrium (Figure 1B: MV, mitral valve; TV, tricuspid valve), from the right ventricle (Figure 1C), and lastly, a lateral view after offline subtraction of the anterolateral wall of the right ventricle (Figure 1D). The surgical analysis confirmed the 3D echocardiographic findings and additionally disclosed severe involvement of the subvalvular apparatus and endocardial deposit of pe...

eyelashes (Fig. 1C) hyperkeratosis of lid margin with folliculosis, conjuctival congestion and follicular reaction. The child had alopecia (Fig. 1D). Corneal infiltration was present at the level of epithelium and sub-epithelium (Fig. 2). On the basis of above features, he was diagnosed of ichthyosis follicularis alopecia and photophobia (IFAP) syndrome1 that is caused by mutation in MBTPS2 gen...