visceral leishmaniasis (vl) is a zoonotic disease caused by leishmania species. dogs are considered to be the main reservoir of vl. a number of methods and antigen-based assays are used for the diagnosis of leishmaniasis. however, currently available methods are mainly based on direct examination of tissues for the presence of parasites, which is highly invasive. a variety of serological tests ...

a three-fold decrease of the in vitro ability of serum proteins to bind naproxen was shown in patients with cirrhosis of the liver compared to healthy individuals. this decrease was caused by quantitative changes in serum proteins in the sera of patients with liver damage. lower doses of naproxen are therefore suggested in the treatment of patients with liver dysfunction.

background: hepatitis c virus (hcv) infection is one of the most prevalent infectious diseases responsible for high morbidity and mortality worldwide. therefore, designing new and effective therapeutics is of great importance. the aim of the current study was to construct a dna vaccine containing structural proteins of hcv and evaluation of its expression in a eukaryotic system. methods: struct...

phase transition from vegetative to reproductive growth is an important character for winter wheat under cold conditions because it decreases the ability of wheat plants to maintain frost tolerance. reproductive development in winter wheat is triggered by fulfillment of vernalization requirements. this study was conducted to determine the inter-relationship between developmental stages and free...

abstract background: sp-a and sp-d are hydrophilic proteins which regulate the inflammatory response of the lung. pasteurella multocida is one of the most common bacteria isolated from calves suffering from shipping fever pneumonia, one of the most problems in dairy herds. objective: evaluation of surfactant content may provide a valuable diagnostic tool for detection of calf pneumonia due to p...

a proteomic approach was conducted to further understand the mechanism of plant responses to salinity in hordeum bulbosom. three-week-old seedlings were treated with 300 mm of nacl for 21 days. total proteins of fourth leaf were extracted and separated by two-dimensional gel electrophoresis. more than 500 protein spots were reproducibly detected, including 46 spots that were up-regulated and 16...

protein s (ps) is an antithrombotic plasma protein that plays essential roles in limiting thrombus formation in the anticoagulant system. protein s deficiency is related with recurrent thrombosis. here, the authors report a case of a term neonate with severe ps deficiency in year 2015, imam hospital, tehran, iran, that had seizures and intraventricular hemorrhage (ivh) since the age of 3 days. ...

This study was performed in order to evaluate the effects of irrigation and application of Zn fertilizer on  seed storage proteins  in chickpea, Azad cultivar. Experiment was performed in an factorial using randomized complete block design with three replications. In this experiment, two factor consist of irrigation in three levels (I1= non irrigation and I2= irrigation in...

Background/Objective: Development of a new enzyme-linked immunosorbent assay (ELISA) for screening human blood serum and plasma for antibodies to human immunodeficiency virus type 1 (HIV1) and type 2 (HIV2) as HIV1/2REC ELISA diagnostic kit based on E. coli derived soluble recombinant proteins. Methods: Polypeptides corresponding to HIV1 gp41 and HIV2 gp36 immunodominant regions and HIV1 gag we...