The IL21R gene is comprised of 9 exons (+2 alternative first exons), spanning 48.4kb on chromosome 16p11 (Parrish-Novak, 2000). The human IL21R promoter region, contained within nucleotides -789 to +195 (relative to the start of exon 1a) induces the high levels of transcription in reporter assays (Ueda, 2002). A critical SP1 binding site is contained in the region from -80 to -20 and is essenti...

BACKGROUND The aim of this study was to assess the differences in microRNA 21 expression among neuroblastoma (NB), embryonic tissue, and normal adrenal tissue and to identify correlations between microRNA 21 expression, the biological features of the tumor, and prognosis. METHODS A total of 70 patients with NB were selected from December 2005 and December 2007. Real-time polymerase chain reac...

Angina of Effort-Srivastava et al. BWDIHLJOURNAL 725 obtained in the final 14 days of each 21-day period. The patients' own general assessment of each treatment is based upon the whole 21-day periods and scored on a five-point scale in the following way:-1 worsening of the angina; + 1, + 2, and +3 indicating slight, moderate, and marked improvement respectively; and 0 showing that the condition...

The canine pancreatic specific lipase is available as a SNAP cPL and as a quantitative test Spec cPL. Sensitivity of Spec cPL concentrations vary for mild pancreatitis (21%), moderate to severe pancreatitis (71%), and pancreatitis overall (64–94%). Currently, serum cPL concentration is considered the most specific serum biomarker for the diagnosis of pancreatitis in dogs. Specificities range fr...

A total of 3 strains were found with potential antibacterial activity. The MMKK5 strain showed moderate, good and excellent growth in GAA broth during 7, 14 and 21 day of incubation respectively while in starch-casein broth weak growth observed in 7 days incubation but finally at twenty one days showed excellent growth. MMKK2 showed moderate to good growth up to 21 days of incubation. Whereas, ...

OBJECTIVE The objective of this pilot study was to compare the efficacy of Emotional Freedom Techniques (EFT) with that of Cognitive-Behavioral Therapy (CBT) in reducing adolescent anxiety. DESIGN Randomized controlled study. SETTINGS This study took place in 10 schools (8 public/2 private; 4 high schools/6 middle schools) in 2 northeastern states in the United States. PARTICIPANTS Sixty-...

OBJECTIVE To quantify the prevalence of Irritable Bowel Syndrome (IBS) among medical students of King Saud bin Abdulaziz University for Health Sciences (KSAU-HS) and to observe the association between anxiety and IBS. METHODS This cross-sectional observational study conducted during academic year 2015-2016 has used two self-administered, pre-validated questionnaires: Depression Anxiety Stress...

The aim of this study was to evaluate the biocompatibility of sealers used in apical surgery in rat subcutaneous tissue. Sterile polyethylene tubes were filled with the following sealers: Sealapex, Sealapex with addition of zinc oxide, Sealer 26, Sealer 26 with thicker consistency (greater powder-to-resin ratio) and White MTA. The tubes were implanted in the dorsum of male rats and after 7, 21 ...